在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Ephrin-A2 (Efna2)

  • 中文名稱(chēng):
    小鼠Efna2重組蛋白
  • 貨號(hào):
    CSB-YP007461MO
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    小鼠Efna2重組蛋白
  • 貨號(hào):
    CSB-EP007461MO
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    小鼠Efna2重組蛋白
  • 貨號(hào):
    CSB-EP007461MO-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    小鼠Efna2重組蛋白
  • 貨號(hào):
    CSB-BP007461MO
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    小鼠Efna2重組蛋白
  • 貨號(hào):
    CSB-MP007461MO
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Efna2; Elf1; Epl6; Eplg6; Lerk6Ephrin-A2; CEK7-ligand; CEK7-L; ELF-1; EPH-related receptor tyrosine kinase ligand 6; LERK-6
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    21-184
  • 氨基酸序列
    RNEDPARANA DRYAVYWNRS NPRFQVSAVG DGGGYTVEVS INDYLDIYCP HYGAPLPPAE RMERYILYMV NGEGHASCDH RQRGFKRWEC NRPAAPGGPL KFSEKFQLFT PFSLGFEFRP GHEYYYISAT PPNLVDRPCL RLKVYVRPTN ETLYEAPEPI FTSN
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
  • 基因功能參考文獻(xiàn):
    1. The ephrin-A2/-A3 DKO mice have utility as a novel ASD model with an emphasis on sensory abnormalities and restricted, repetitive behavioral symptoms. PMID: 25281279
    2. The results of this study suggested that majority of the changes observed ephrin-A2 and ephrin-A5 KO mice appear to be mediated by the effects on motor neurons and their muscle targets, rather than changes in auditory sensitivity. PMID: 25200515
    3. Ephrin-A2 and -A3 are negative regulators of the proliferative and neurogenic potentials of Muller cells. PMID: 25269910
    4. Ephrin-A2 and Ephrin-A5 are important for the functional development of cutaneous innervation. PMID: 25243788
    5. At high frequencies, the ephrin-A2A5(-/-) mice exhibited thresholds that were significantly lower than in wild-type mice by approximately 20 dB, suggesting ephrin-A2 and ephrin-A5 may have frequency-specific effects on the auditory system. PMID: 24457350
    6. In EphA4 mutant mice, as well as after ephrin A2 knockdown using in utero electroporation, we found delayed interneuron migration at embryonic stages. PMID: 24381199
    7. ephrin-A2 regulates experience-dependent, NMDA receptor-mediated synaptic pruning through glial glutamate transport during maturation of the mouse cortex. PMID: 24094103
    8. EphA2-mediated mesenchymal-amoeboid transition induced by endothelial progenitor cells enhances metastatic spread due to cancer-associated fibroblasts. PMID: 22903544
    9. Implicate EphA2 as a novel proinflammatory mediator and potential regulator of atherosclerotic plaque development. PMID: 22247258
    10. The results of this study suggested that the misexpression of ephrin-A2 may lead to abnormal connectivity in regions known for their involvement in reversal learning and perseverative behaviours. PMID: 20100519
    11. Tiam1 is required for neurite outgrowth induced by both ephrin-B1-mediated reverse signaling and EphA2-mediated forward signaling PMID: 14988728
    12. ephrin-A2 expression was observed in synapses during reactive synaptogenesis PMID: 15710390
    13. identification of ephrin-A2 and EphA7 as negative regulators of progenitor cell proliferation reveals a novel mechanism to control cell numbers in the brain PMID: 15713841
    14. In mice deficient for ephrin-A2, A3 and A5, eye-specific inputs segregated but shape and location of eye-specific layers were profoundly disrupted. Ephrin-As and neural activity act together to control patterning of eye-specific retinogeniculate layers. PMID: 16025107
    15. Misalignment of ipsilateral and contralateral visual information in the superior colliculus results in inappropriate terminations in ephrin-A2/A5(-/-) double knock-out mice and suggests a role for ephrin-As in integrating convergent visual inputs. PMID: 18632942
    16. Bidirectional ephrinA2-EphA2 signaling regulates bone remodeling at the initiation phase. PMID: 19299512

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Ephrin family
  • 組織特異性:
    Expressed in myogenic progenitor cells.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 国产片a国产片免费看视频| 成 人 在 线 免费观看| 亚洲女教师丝祙在线播放| 亚洲精品久久66国产高清| 亚洲欭美日韩颜射在线| 国产精品欧美久久久久久日本一道| 色情久久久av熟女人妻网站| 玩肥熟老妇bbw视频| 亚洲精品色情app在线下载观看| 鲁大师在线视频播放免费观看| 久久久www成人免费精品| 中文字幕乱码亚洲无线码三区| 西西人体午夜大胆无码视频| 国产av熟女一区二区三区| 亚洲国产精品久久网午夜| 亚洲精品拍拍央视网出文| 久久九九国产精品怡红院| 狠狠色综合激情丁香五月| 国产精品福利视频一区| 中文成人无码精品久久久动漫 | 狠狠做五月深爱婷婷| 国产精品网站在线观看免费传媒| av大片在线无码永久免费| 日本一区二区无卡高清视频| 午夜dj在线观看高清在线视频完整版| 99精品电影一区二区免费看| 不卡无码av一区二区三区| 国产精品白丝av网站| 18黄暴禁片在线观看| 欧美丰满熟妇xxxx| 精品国产乱码久久久久久乱码| 在线观看片免费视频无码| 国产肥白大熟妇bbbb视频| 亚洲人成无码区在线观看| 久久天天躁狠狠躁夜夜2o2o| 国产精品久久久久久久免费看| 国产精品一区二区久久精品| 大香伊蕉日本一区二区| 国产精品99久久久久久久女警| 国产午夜精品一区二区三区嫩草| 欧美人成视频在线视频|