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Recombinant Mouse EP300-interacting inhibitor of differentiation 2 (Eid2)

  • 中文名稱(chēng):
    小鼠Eid2重組蛋白
  • 貨號(hào):
    CSB-YP761545MO
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    小鼠Eid2重組蛋白
  • 貨號(hào):
    CSB-EP761545MO
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    小鼠Eid2重組蛋白
  • 貨號(hào):
    CSB-EP761545MO-B
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    小鼠Eid2重組蛋白
  • 貨號(hào):
    CSB-BP761545MO
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    小鼠Eid2重組蛋白
  • 貨號(hào):
    CSB-MP761545MO
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Eid2
  • Uniprot No.:
  • 別名:
    Eid2; Cri2EP300-interacting inhibitor of differentiation 2; EID-2; CREBBP/EP300 inhibitor 2; EID-1-like inhibitor of differentiation 2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-236
  • 氨基酸序列
    MSQLPAVSSA PQTGAASRDR RLPQAEVGGG RRALPGPARP GETRGRPMAA AREGPAAPAA AARGGRVAAA REGRAAAARG GPGAAPRGGA AAREGPAAAA ASREARMAEV ARLLGDPLEE EAPEGRPRSR AGGLAAMPYM RFRHPLSVLG INYQQFLRHY LENYPIAPGR IQELEERRRR FVEACRAREA AFDIEYLRNP QRVDFDILTF TIALTASEVI NPLIEELGCD KFIHRE
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
  • 基因功能參考文獻(xiàn):
    1. Unlike that of EID-2, the C-terminus, but not the N-terminus, of EID-3 was required for nuclear localization. EID-3 formed a homodimer or heterodimer with EID-2 PMID: 15970276
  • 亞細(xì)胞定位:
    Nucleus.
  • 組織特異性:
    Expressed in heart, brain, kidney and pancreas. Not detected in placenta.
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: mmu:386655

    UniGene: Mm.258201



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