在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse E3 ubiquitin-protein ligase RBX1 (Rbx1)

  • 中文名稱:
    小鼠Rbx1重組蛋白
  • 貨號(hào):
    CSB-YP019496MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rbx1重組蛋白
  • 貨號(hào):
    CSB-EP019496MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rbx1重組蛋白
  • 貨號(hào):
    CSB-EP019496MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rbx1重組蛋白
  • 貨號(hào):
    CSB-BP019496MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rbx1重組蛋白
  • 貨號(hào):
    CSB-MP019496MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Rbx1; E3 ubiquitin-protein ligase RBX1; EC 2.3.2.27; EC 2.3.2.32; E3 ubiquitin-protein transferase RBX1; RING finger protein 75; RING-box protein 1; Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1; N-terminally processed]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-108
  • 氨基酸序列
    MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM DLCIECQANQ ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE WEFQKYGH
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.
  • 基因功能參考文獻(xiàn):
    1. Downregulation of Rbx1 caused accumulation of Emi1. PMID: 23874827
    2. a model by which N-terminal cleavage of RBX1 impairs its activity and promotes susceptibility to ER stress induction. PMID: 22822056
    3. in vivo physiological function of RBX1 is to ensure cell proliferation by preventing p27 accumulation during the early stage of embryonic development PMID: 19325126
  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    RING-box family
  • 組織特異性:
    Widely expressed.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 日本熟妇色高清免费视频| 日本三级欧美三级人妇视频黑白配| 最近免费中文字幕中文高清百度| 国产 高清 无码 在线播放| 97人人超碰国产精品最新| 国产成人亚洲综合无码| 国产一区二区| 国产真实伦在线观看视频| 天堂www中文资源| 男人和女人做爽爽视频| 无码人中文字幕| 国产爆乳无码av在线播放| 国产剧情无码播放在线看 | 日本精品人妻无码77777| 岛国片人妻三上悠亚| 亚洲国产av无码一区二区三区 | 无码无套少妇毛多69xxx| 无套内射视频囯产| 人人人插人人费| 国产免费极品av吧在线观看 | 蜜臀aⅴ国产精品久久久国产老师| 久久综合色一综合色88| 日本日本乱码伦专区| 性欧美熟妇videofreesex| 国精产品一区二区三区| 亚洲色偷偷偷网站色偷一区| 免费国产裸体美女视频全黄| 99这里只有精品| 无码中文字幕人妻在线一区| 亚洲人成在线观看网站无码| 国产精品三级在线观看无码| 在线亚洲欧美日韩精品专区| 人妻性奴波多野结衣无码| 国产精品久久久午夜夜伦鲁鲁 | 全部孕妇毛片丰满孕妇孕交| 亚洲a∨国产av综合av| 亚洲精品久久国产精品| 人人超人人超碰超国产97超碰| 国产伦子沙发午休系列资源曝光| 久久99国产精品二区| 一二三四社区在线中文视频|