在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (Dlat)

In Stock
  • 中文名稱:
    小鼠Dlat重組蛋白
  • 貨號:
    CSB-EP804374MOa0
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP804374MOa0 could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Dlat.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Dlat
  • Uniprot No.:
  • 別名:
    Dlat; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; mitochondrial; EC 2.3.1.12; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Pyruvate dehydrogenase complex component E2; PDC-E2; PDCE2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    62.8 kDa
  • 表達區域:
    86-642aa
  • 氨基酸序列
    SLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDLAAAAAPQAAPAAAPAPAAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVAAVPPTPQPVAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFVPSKAAPAAAAAMAPPGPRVAPAPAGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKGKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITMLL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:
        DLAT是線粒體內的一種蛋白質,它是丙酮酸脫氫酶復合物(Pyruvate Dehydrogenase Complex,簡稱 PDC)的一部分,負責催化乙酰輔酶A的合成。PDC是一種分布于線粒體基質中的多酶復合體,通過催化丙酮酸的氧化脫羧反應生成乙酰輔酶A,有效連接糖酵解和三羧酸循環。在科研上,DLAT的重組蛋白被廣泛用于各種研究中。例如,它被用于加速信號傳導研究,因為它是細胞內復雜世界的關鍵組成部分。此外,DLAT的重組蛋白也被用于研究腫瘤免疫逃逸,因為研究發現,丙酮酸脫氫酶復合物E1組分α亞基(PDHE1α)存在豐富的胞質定位,并且在腫瘤免疫逃逸中起著重要的作用。
        華美生物提供大腸桿菌表達系統制備的全長DLAT重組蛋白,可幫助您更好地理解細胞內的復雜機制,有望為疾病的治療提供新的思路和方法。
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻:
    1. These data reveal a central role for Dlat in the metabolic program regulated by E4F1 in basal keratinocytes. PMID: 27621431
    2. On the basis of our ChIP data and these previous findings, we hypothesize that PDC may modulate STAT5's ability to regulate gene expression by controlling histone or STAT5 acetylation PMID: 28982698
    3. breach of tolerance to PDC-E2 is probably the first event in the natural history of primary biliary cirrhosis in genetically susceptible hosts. PMID: 24128311
    4. a novel function of pyruvate dehydrogenase complex E2 in the nucleus in up-regulating the transactivating ability of STAT5 PMID: 21397011
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    2-oxoacid dehydrogenase family
  • 數據庫鏈接:


主站蜘蛛池模板: 四虎亚洲精品无码| 亚洲熟女乱色综合亚洲图片| 国产免费无码一区二区视频| 精品亚洲欧美自拍| 成人免费无码大片a毛片户外| 亚洲第一页综合图片自拍| 亚洲成在人线视av| 亚洲aⅴ无码国精品中文字慕| 国产suv精品一区二区6| 亚洲色成人网站永久| 色琪琪丁香婷婷综合久久| 久久精品国产69国产精品亚洲| 国产精品视频白浆免费视频| 国产在线精品视频二区| 男女高潮喷水在线观看| 成人区人妻精品一区二区三区| (无码视频)在线观看| 亚洲最大av一区二区三区| 成人无码视频免费播放| 国精无码欧精品亚洲一区| 国产乱子经典视频在线观看 | 亚洲色成人www永久网站| 日本久久综合久久综合| 最新无码a∨在线观看| 少妇的肉体在线观看| 人人色在线视频播放| 国产无遮挡色视频免费观看性色| 色优久久久久综合网鬼色| 国产精品爽爽v在线观看无码| 久久亚洲精品无码网站| 精品无码一区在线观看| 无码爆乳护士让我爽| 欧美一区二区三区激情| 青青青国产在线观看资源| 亚洲国产成人无码精品| 天躁夜夜躁狼狠躁| 午夜福利片手机在线播放| 99久久精品费精品国产一区二| 亚洲日韩国产av无码无码精品| 西西人体大胆4444www| 亚洲欧美国产国产一区二区三区 |