在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Desmoplakin (Dsp), partial

Recombinant Mouse Desmoplakin (Dsp), partial

  • 中文名稱：
    小鼠Dsp重組蛋白
  • 貨號：
    CSB-YP007208MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Dsp重組蛋白
  • 貨號：
    CSB-EP007208MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Dsp重組蛋白
  • 貨號：
    CSB-EP007208MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Dsp重組蛋白
  • 貨號：
    CSB-BP007208MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Dsp重組蛋白
  • 貨號：
    CSB-MP007208MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dsp
  • Uniprot No.：
  • 別名：
    Dsp; Desmoplakin; DP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
  • 基因功能參考文獻：
    1. Deletion of Dsp under the transcriptional regulation of the CSPG4 locus led to phenotype resembling the human cardiocutaneous syndromes. PMID: 29018034
    2. Conditional heterozygous deletion of Dsp in mice led to increased fibroadipogenesis in the heart and mild cardiac dysfunction. PMID: 27121621
    3. Our data suggest that endurance exercise accelerates arrhythmogenic ventricular cardiomyopathy pathogenesis in transgenic DSP mice PMID: 26545710
    4. GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics. PMID: 25733715
    5. These data indicate a function of desmoplakin in motor nerve regeneration by linking N-cadherin to intermediate filaments in regenerating motor axons. PMID: 25496840
    6. A loss of desmoplakin expression led to an abnormal distribution of Cx43 and Nav1.5, while scrapeloading dye/transfer revealed a decrease in dye transfer in DSP siRNAtreated cells. PMID: 23877755
    7. the desmosomal protein desmoplakin is not essential for cell adhesion in the intestinal epithelium. PMID: 22238362
    8. Loss of desmoplakin expression and resultant disruption of desmosomal adhesion can promote increased local tumor invasion independent of adherens junction status. PMID: 20862307
    9. desmoplakin has a role in capillary formation PMID: 15190119
    10. desmocollins show a higher degree of similarity to the classical cadherins, such as E-cadherin, than to the desmogleins. PMID: 15346771
    11. Data show suppression of desmoplakin expression leads to nuclear localization of plakoglobin and a 2-fold reduction in canonical Wnt/beta-catenin signaling through Tcf/Lef1 transcription factors. PMID: 16823493
    12. DSP expression in cardiomyocytes is crucial for maintaining cardiac tissue integrity, and DSP abnormalities result in ARVD/C by cardiomyocyte death, changes in lipid metabolism, and defects in cardiac development. PMID: 16917092
    13. Results demonstrate a differentiation-specific rearrangement of the microtubule cytoskeleton in epidermis, and defines an essential role for desmoplakin in the process. PMID: 17227889

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane.
  • 蛋白家族：
    Plakin or cytolinker family
  • 數據庫鏈接：


主站蜘蛛池模板： 无码h黄动漫在线播放网站| 2018高清日本一道国产-在| 在线永久无码不卡av| 亚洲免费观看视频| 高清中文字幕在线a片| 97人妻天天爽夜夜爽二区| 久久国产美女精品久久| 黄网站免费永久在线观看下载| 永久免费观看美女裸体视频的网站| 国产一区日韩二区欧美三区| 国产成人一区二区三区别| 亚洲高清无在码在线电影不卡| 老司机深夜18禁污污网站| 日本三级带日本三级带黄| 精品国产一区二区三区久久| 国产成人无码av| 人妻综合专区第一页| 精品一区二区三区在线播放视频| 久久无码精品一区二区三区| 少妇高潮惨叫久久久久久| 在线岛国片免费无码av| 免费三级现频在线观看播放| 特级做a爰片毛片免费看| 国产成人无码免费看片软件| 麻豆国产在线精品国偷产拍| 日韩精品一区二区三区vr| 国精品人妻无码一区二区三区性色| 国产乱子伦精品无码码专区 | 真人性生交免费视频| 老司机性色福利精品视频| 国产乱子伦在线一区二区| 成 人片 黄 色 大 片| 一区二区三区中文字幕| 亚洲 欧美 另类图片| 中文字幕日本乱码仑区在线| 久久久久99精品成人片试看| 18禁女裸乳扒开免费视频| 精品国产乱码久久久久久乱码| 97在线观看播放| 精品夜夜澡人妻无码av蜜桃| 成人国产精品无码网站|