Recombinant Mouse Delta-aminolevulinic acid dehydratase (Alad)

中文名稱：

Recombinant Mouse Delta-aminolevulinic acid dehydratase(Alad)
貨號：

CSB-YP001558MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Delta-aminolevulinic acid dehydratase(Alad)
貨號：

CSB-EP001558MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Delta-aminolevulinic acid dehydratase(Alad)
貨號：

CSB-EP001558MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Delta-aminolevulinic acid dehydratase(Alad)
貨號：

CSB-BP001558MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Delta-aminolevulinic acid dehydratase(Alad)
貨號：

CSB-MP001558MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Alad
Uniprot No.：

P10518
別名：

Alad; Lv; Delta-aminolevulinic acid dehydratase; ALADH; EC 4.2.1.24; Porphobilinogen synthase
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達(dá)區(qū)域：

1-330
氨基酸序列

MHHQSVLHSG YFHPLLRSWQ TAASTVSASN LIYPIFVTDV PDDVQPIASL PGVARYGVNQ LEEMLRPLVE AGLRCVLIFG VPSRVPKDEQ GSAADSEDSP TIEAVRLLRK TFPSLLVACD VCLCPYTSHG HCGLLSENGA FLAEESRQRL AEVALAYAKA GCQVVAPSDM MDGRVEAIKA ALLKHGLGNR VSVMSYSAKF ASCFYGPFRD AAQSSPAFGD RRCYQLPPGA RGLALRAVAR DIQEGADMLM VKPGLPYLDM VREVKDKHPE LPLAVYQVSG EFAMLWHGAQ AGAFDLRTAV LETMTAFRRA GADIIITYFA PQLLKWLKEE
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
基因功能參考文獻(xiàn)：
1. this study demonstrated for the first time the involvement of striatal delta-ALA-D activity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and its correlation with the MPO activity. PMID: 27650074
2. The data supports the hypothesis that ALAD, an important enzyme for heme synthesis, is also important as a proteasome interacting protein. PMID: 21640720
3. Delta-ALA-D from D. melanogaster and M.musculus has a different profile of optimum pH and different sensitivity for diphenyl diselenide and lead, two inhibitors. PMID: 17936691
蛋白家族：

ALAD family
數(shù)據(jù)庫鏈接：

KEGG: mmu:17025

STRING: 10090.ENSMUSP00000030090

UniGene: Mm.6988