在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse DNA fragmentation factor subunit beta (Dffb)

Recombinant Mouse DNA fragmentation factor subunit beta (Dffb)

  • 中文名稱：
    小鼠Dffb重組蛋白
  • 貨號：
    CSB-YP006738MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Dffb重組蛋白
  • 貨號：
    CSB-EP006738MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Dffb重組蛋白
  • 貨號：
    CSB-EP006738MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Dffb重組蛋白
  • 貨號：
    CSB-BP006738MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Dffb重組蛋白
  • 貨號：
    CSB-MP006738MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Dffb; Cad; DNA fragmentation factor subunit beta; EC 3.-.-.-; Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; DNA fragmentation factor 40 kDa subunit; DFF-40
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-344
  • 氨基酸序列
    MCAVLRQPKC VKLRALHSAC KFGVAARSCQ ELLRKGCVRF QLPMPGSRLC LYEDGTEVTD DCFPGLPNDA ELLLLTAGET WHGYVSDITR FLSVFNEPHA GVIQAARQLL SDEQAPLRQK LLADLLHHVS QNITAETREQ DPSWFEGLES RFRNKSGYLR YSCESRIRGY LREVSAYTSM VDEAAQEEYL RVLGSMCQKL KSVQYNGSYF DRGAEASSRL CTPEGWFSCQ GPFDLESCLS KHSINPYGNR ESRILFSTWN LDHIIEKKRT VVPTLAEAIQ DGREVNWEYF YSLLFTAENL KLVHIACHKK TTHKLECDRS RIYRPQTGSR RKQPARKKRP ARKR
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
  • 基因功能參考文獻：
    1. Dff40 expression is upregulated in atherosclerotic plaque. Dff40 deficiency inhibited high-fat diet-induced atherosclerosis, as evidenced by decreased atherosclerotic plaques, inhibited inflammatory response, and macrophage apoptosis, as well as enhanced stability of plaques. PMID: 28007744
    2. the highest order of chromatin compaction observed in the later steps of caspase-dependent apoptosis relies on DFF40/CAD-mediated DNA damage by generating 3'-OH ends in single-strand rather than double-strand DNA nicks/breaks PMID: 23430749
    3. The thymus of DNase II(-/-)CAD(-/-) embryos contained many foci carrying undigested DNA and the cellularity was severely reduced due to a block in T cell development. PMID: 12524536
    4. In transfected HeLa cells, transiently expressed DFF associates with chromatin, suggesting that DFF could be activated during apoptosis in a DNA-bound state PMID: 15572351
    5. Interactions identified here between mouse liver histone H1 carboxyl-terminal domain and DFF40/CAD target and activate linker DNA cleavage during the terminal stages of apoptosis. PMID: 15910001
    6. The results suggest that CAD protein may be preferentially degraded by the ubiquitin-proteasome system in the absence of its inhibitor (ICAD) to maintain protein quality control. PMID: 18178165
    7. A los of caspase-activated DNASE enhances tumorigenesis induced by a chemical carcinogen in a model of skin carcinogenesis in mice. PMID: 19541853

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 少妇人妻无码专区毛片| 欧美成人一区二区三区| 成人区精品一区二区不卡| 在线人视频观看免费| 吃奶呻吟张开双腿做受在线播放| 国产精品成人av片免费看| 国产99在线 | 亚洲| 伊人无码精品久久一区二区| 国产精品99久久久久久宅男小说 | 少妇大叫太大太粗太爽了a片小说 爱性久久久久久久久 | 狠狠躁夜夜躁人人爽天天天天| 国产激情久久久久影院老熟女免费| 少妇与子乱在线观看| 日本xxxx丰满老妇| 无码精品黑人一区二区三区| 欧美伊人久久大香线蕉综合| 人妻被按摩师玩弄到潮喷| 99久久无色码中文字幕人妻| 日本精品aⅴ一区二区三区| 在线视频网站www色| 东京热人妻无码一区二区av| 久久ee热这里只有精品| 免费网站看sm调教视频| 日日噜噜噜夜夜爽爽狠狠视频| 亚洲人成网站在线播放小说| 狠狠噜狠狠狠狠丁香五月| 九九综合va免费看| 色噜噜狠狠一区二区三区| 国产真实野战在线视频| 成人无码精品免费视频在线观看| 国产精品久久久福利| 久久精品欧美日韩精品| 免费看撕开奶罩揉吮奶头视频| 一本无码人妻在中文字幕| 欧美亚洲色综久久精品国产| 国产一二三四区乱码免费| 国产精品无码a∨麻豆| 久在线观看福利视频| 国产98色在线 | 国| 精品免费国偷自产在线视频| 国产精品国产亚洲精品看不卡|