在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse DNA excision repair protein ERCC-8 (Ercc8)

Recombinant Mouse DNA excision repair protein ERCC-8 (Ercc8)

  • 中文名稱：
    小鼠Ercc8重組蛋白
  • 貨號：
    CSB-YP804034MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ercc8重組蛋白
  • 貨號：
    CSB-EP804034MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ercc8重組蛋白
  • 貨號：
    CSB-EP804034MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ercc8重組蛋白
  • 貨號：
    CSB-BP804034MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ercc8重組蛋白
  • 貨號：
    CSB-MP804034MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ercc8; Ckn1; CsaDNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA homolog
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-397
  • 氨基酸序列
    MLSFLSARQS GLEDPLRLRR AQSTRRVLGL ELNKDRDVER IHGSGVNTLD IEPVEGRYML SGGSDGVVVL YDLENASRQP HYTCKAVCSV GRSHPDVHKY SVETVQWYPH DTGMFTSSSF DKTLKVWDTN TLQAADVFNF EETVYSHHMS PAATKHCLVA VGTRGPKVQL CDLKSGSCSH ILQGHRQEIL AVSWSPRHDY ILATASADSR VKLWDVRRAS GCLLTLDQHN GKKSQAAESA NTAHNGKVNG LCFTSDGLHL LTIGTDNRMR LWNSSSGDNT LVNYGKVCND SRKGLQFAVS CGCSSEFVFV PHGSTIAVYA VHSGERLAML KGHYKSVDCC VFQPNFQELY SGSRDCNILA WVPPSYEPVP DDDDEAPAKS QLNPAFADAW SSSDEDG
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription-coupled repair complex which removes RNA polymerase II-blocking lesions from the transcribed strand of active genes. Plays a role in DNA single-strand and double-strand breaks (DSSBs) repair; involved in repair of DSSBs by non-homologous end joining (NHEJ).
  • 基因功能參考文獻：
    1. This study demonistrated that Cockayne syndrome group A deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice. PMID: 25762674
    2. MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csa(-/-) mice PMID: 20100872
    3. difference in oxidative DNA damage sensitivity between CSA- and CSB-deficient cell lines and mice PMID: 15340056
  • 亞細胞定位：
    Nucleus. Nucleus matrix.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 成人性生交大片免费卡看| 日韩欧美在线综合网| 久久av一区二区三区| 欧美一进一出抽搐大尺度视频| 九一九色国产| 一本大道久久东京热无码av| 在线观看麻豆国产成人av在线播放 | 国产成a人亚洲精品无码久久网| 精品偷自拍另类在线观看| 国产α片免费观看在线人| 色综合亚洲一区二区小说| 999国内精品永久免费观看| 久久无码高潮喷水| 欧美奶涨边摸边做爰视频| 天天做天天爱天天爽综合网| 无码av免费永久免费永久专区| av色国产色拍| 久久久久久亚洲综合影院| 极品新婚夜少妇真紧| 亚洲色婷婷一区二区三区| 国产亚洲精品久久久久秋霞| 看国产黄大片在线观看| 亚洲中文字幕乱码一区| 在线播放国产麻豆va剧情| 亚洲精品无播放器在线播放| 成在人线av无码免费| 欧美成人看片一区二区| 毛片免费观看天天干天天爽| 牛和人交videos欧美| 色狠狠成人综合网| 正在播放重口老熟女露脸| 国产超碰人人做人人爽av| 色欲网天天无码av| 性色av蜜臀av色欲av| 婷婷五月婷婷五月| 大香伊蕉日本一区二区| 内射女校花一区二区三区| 极品尤物一区二区三区| 日本高清熟妇老熟妇| 国产精品禁忌a片特黄a片| 欧美黑吊大战白妞|