在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse DCN1-like protein 1 (Dcun1d1)

Recombinant Mouse DCN1-like protein 1 (Dcun1d1)

  • 中文名稱：
    Recombinant Mouse DCN1-like protein 1(Dcun1d1)
  • 貨號：
    CSB-YP879468MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse DCN1-like protein 1(Dcun1d1)
  • 貨號：
    CSB-EP879468MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse DCN1-like protein 1(Dcun1d1)
  • 貨號：
    CSB-EP879468MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse DCN1-like protein 1(Dcun1d1)
  • 貨號：
    CSB-BP879468MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse DCN1-like protein 1(Dcun1d1)
  • 貨號：
    CSB-MP879468MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dcun1d1
  • Uniprot No.：
  • 別名：
    Dcun1d1; Dcun1l1; Rp42; Tes3DCN1-like protein 1; DCUN1 domain-containing protein 1; Defective in cullin neddylation protein 1-like protein 1; Testis-specific protein 3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-259
  • 氨基酸序列
    MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYT RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS SMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
  • 基因功能參考文獻：
    1. Data (including data from studies using cells cultured from knockout mice) suggest that Sccro neddylates Cul3 with Nedd8, promoting Cul3/Klhl21 complex formation and localization of Cul3 during telophase. (Sccro = squamous cell carcinoma-related oncogene; Cul3 = cullin 3; Nedd8 = neural precursor cell expressed, developmentally down-regulated protein 8; Klhl21 = kelch-like protein 21) PMID: 28620047
    2. SCCRO family members cooperatively regulate neddylation and cell proliferation. PMID: 26792857
    3. The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity. PMID: 25411243
    4. in the nucleus, SCCRO enhances recruitment of Ubc12 to Cul1 to promote neddylation PMID: 21247897
    5. SCCRO promotes glioma formation and malignant progression. PMID: 20563250

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Highly expressed in testis. Also expressed in brain, heart, liver, skeletal muscle and kidney. In brain, preferentially expressed in the telencephalon ventricular and subventricular zones, albeit at low levels. In adult testis, expressed in cells above se
  • 數據庫鏈接：


主站蜘蛛池模板： 一本大道东京热无码视频| 国产精品久久久久久久| 7777久久亚洲中文字幕| 天堂俺去俺来也www色官网| 亚洲精品suv精品一区二区| 夜夜夜夜猛噜噜噜噜噜试看| 亚洲人成人网站在线观看| 欧美日韩精品一区二区三区不卡 | 水蜜桃色314在线观看| 人人妻人人添人人爽欧美一区| 一本一本久久a久久综合精品蜜桃 国产精品人妻久久毛片高清无卡 成视频年人黄网站视频福利 | 国产95在线 | 欧美| 国产成人无码午夜福利在线直播| 婷婷色怡春院| 成人亚洲性情网站www在线观看| 插插无码视频大全不卡网站| 日本两人免费观看的视频| 99热这里只有是精品2| 中文无码久久精品| 精品久久久久久无码专区不卡| 亚洲国产欧美在线人成人| 免费无码av片流白浆在线观看| 国产国产乱老熟女视频网站97| 久久久久爽爽爽爽一区老女人| 色惰日本视频网站www| 天堂…中文在线最新版在线 | 久久人人爽人人爽人人片av| 国产最新精品自产在线观看| 国产黄在线观看免费观看软件| 亚洲成a人片在线观看www| 无码专区3d动漫精品免费| 亚洲va在线va天堂xxxx| 国产成人一区二区不卡免费视频 | 亚洲欭美日韩颜射在线| 国产成人a亚洲精v品无码| 狠狠色噜噜狠狠色综合久| 亚洲精品成人av观看| 国产乱色国产精品播放视频 | 久久综合给合久久狠狠97色| 337p日本欧洲亚洲大胆| 中国xxxx做受视频|