在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse D (1B) dopamine receptor (Drd5), partial

Recombinant Mouse D (1B) dopamine receptor (Drd5), partial

  • 中文名稱：
    小鼠Drd5重組蛋白
  • 貨號：
    CSB-YP804368MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Drd5重組蛋白
  • 貨號：
    CSB-EP804368MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Drd5重組蛋白
  • 貨號：
    CSB-EP804368MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Drd5重組蛋白
  • 貨號：
    CSB-BP804368MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Drd5重組蛋白
  • 貨號：
    CSB-MP804368MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Drd5; D(1B dopamine receptor; D(5 dopamine receptor; Dopamine D5 receptor
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
  • 基因功能參考文獻：
    1. n T2 mice, the mRNA expression of Retn showed a moderate up-regulation (fold change=8.32; p=0.0019) in the adipose tissues. Iapp expression was also significantly up-regulated (fold change=9.78; p=0.012). Moreover, a 6.36-fold up-regulation for Drd5 was observed in the adipose tissues of T2 mice PMID: 29936463
    2. Findings demonstrate the relevant contribution of dopamine receptor D5 (D5R) in memory and suggest a functional interaction of D5R with hippocampal glutamatergic pathways. PMID: 26714288
    3. We suggest that the ability of the dopamine D5 receptor to negatively regulate the renal NADPH oxidase activity and AT1R function may have important implications in the pathogenesis of salt-sensitive blood pressure. PMID: 25716648
    4. This study demonstrated that D5R stimulation contributes to an efficient CD4(+)T-cell-induced early ERK1/2 phosphorylation, and differentiation. PMID: 26025054
    5. The dopamine D5 receptors are particularly important in regulating plasticity of the medial perforant path onto the dentate granule cells. PMID: 25429131
    6. This study demonistrated that the dopamine D5 receptor as a regulator of BDNF and Akt signalling in rodent prefrontal cortex. PMID: 22827965
    7. SNX1 has a crucial role in D(5)R trafficking and SNX1 depletion results in D(5)R dysfunction and thus may represent a novel mechanism for the pathogenesis of essential hypertension PMID: 23152498
    8. By contributing to CD4(+) T cell activation and differentiation to Th17 phenotype, D5R expressed on DCs is able to modulate the development of an autoimmune response in vivo. PMID: 22379034
    9. We propose that ciliary DR5 has functional chemo- and mechano-sensory roles in endothelial cells. PMID: 21709211
    10. There is a role of renal D(5) receptors in blood pressure homeostasis and the pathogenesis of hypertension in mice. PMID: 21051739
    11. Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. PMID: 12486173
    12. Dopamine D5 receptor knockout mice were used to study the role of D5 dopamine receptors in the locomotor-discriminative effects of cocaine. PMID: 12768268
    13. these results confirm and extend the role of the d5 receptor in the modulation of hippocampal acetylcholine release and provide evidence for long-term alteration of hippocampal cholinergic neurotransmission PMID: 15100705
    14. D5 dopamine receptor is found to be expressed in the subcommissural organ (SCO), an ependymal brain gland that is located in the roof of the third ventricle. PMID: 15197646
    15. Dopamine D5 receptor regulates phospholipase D2(PLD2) activity and expression. Hypertension in D5(-/-) mice is associated with increased PLD expression and activity. Impaired D5 receptor regulation of PLD2 may play role in pathogenesis of hypertension. PMID: 15598876
    16. The D(5) receptor mediates discrete topographies of behaviour relating to exploration, and sequential motor coordination; these processes change over the course of interaction with and habituation to the environment. PMID: 15668951
    17. The ability of D5 receptor stimulation to decrease ROS production may explain, in part, the antihypertensive action of D5 receptor activation. PMID: 16352863
    18. the expression and extensive postsynaptic distribution of all known dopamine receptors in spinal cord correspond well with the broad descending dopaminergic projection territory . PMID: 17936519
    19. Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells PMID: 18464932
    20. This review discusses dopamine D5 receptors, which are required for dopamine and selective D(1)-like agonists to induce phospholipase C-mediated phosphoinositide signaling in the mammalian brain. PMID: 19047479
    21. The mRNA level of alpha/beta hydrolase 1 (ABHD1) is significantly upregulated in D5-/- mice. PMID: 19073140
    22. Endogenous dopamine D1/D5 receptor activation decreases NR2A/NR2B ratio of N-methyl-D-aspartate (NMDA) receptor subunit composition at glutamatergic synapses. PMID: 19279248

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 97香蕉碰碰人妻国产欧美| 都市激综合小说区另类区| 忘忧草在线社区www中国中文| 国产又色又爽又刺激在线观看 | 国产精品白浆在线观看免费| 精品一区二区国产在线观看| 国产av国片精品有毛| 无码视频一区二区三区在线观看| 国产精品日韩av在线播放| 国产日韩精品欧美2020区| 国产成+人+综合+亚洲 欧美 | 国产av福利久久| 99亚洲乱人伦aⅴ精品| 成人免费777777被爆出| 国产精品爆乳奶水无码视频免费 | 久热这里只有精品12| 日本公妇乱偷中文字幕| 欧美第一黄网免费网站| 无码动漫性爽xo视频在线观看 | 小sao货水好多真紧h无码视频| 午夜片无码区在线观看视频| 成人免费精品网站在线观看影片| 性色av无码不卡中文字幕| 午夜理论片yy44880影院| 国产麻豆精品传媒av国产婷婷| 韩国主播av福利一区二区| 久久久日韩精品一区二区| 亚洲国产精品成人精品无码区在线 | 亚洲男人第一av网站| 人人做人人爽人人爱| 日韩av片无码一区二区三区| 亚洲另类色区欧美日韩图片| 欧美乱大交xxxxx潮喷l头像| 亚洲国产成人极品综合| 久久久久久亚洲精品a片成人| 777午夜福利理论电影网| 青草视频在线播放| 午夜131美女爱做视频| 亚欧色一区w666天堂| 人妻妺妺窝人体色www聚色窝| 国产av福利第一精品|