Recombinant Mouse Cytohesin-1 (Cyth1)

中文名稱：

Recombinant Mouse Cytohesin-1(Cyth1)
貨號：

CSB-YP874101MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cytohesin-1(Cyth1)
貨號：

CSB-EP874101MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cytohesin-1(Cyth1)
貨號：

CSB-EP874101MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cytohesin-1(Cyth1)
貨號：

CSB-BP874101MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cytohesin-1(Cyth1)
貨號：

CSB-MP874101MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cyth1
Uniprot No.：

Q9QX11
別名：

Cyth1; Pscd1Cytohesin-1; PH; SEC7 and coiled-coil domain-containing protein 1; CLM1; SEC7 homolog A; mSec7-1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區(qū)域：

1-398
氨基酸序列

MEDDDSYVPS DLTAEERQEL ENIRRRKQEL LADIQRLKEE IAEVANEIES LGSTEERKNM QRNKQVAMGR KKFNMDPKKG IQFLIENGLL KNTCEDIAQF LYKGEGLNKT AIGDYLGERD EFSIQVLHAF VELHEFTDLN LVQALRQFLW SFRLPGEAQK IDRMMEAFAQ RYCQCNTGVF QSTDTCYVLS FAIIMLNTSL HNPNVKDKPT VERFIAMNRG INDGGDLPEE LLRNLYESIK NEPFKIPEDD GNDLTHTFFN PDREGWLLKL GGGRVKTWKR RWFILTDNCL YYFEYTTDKE PRGIIPLENL SIREVEDSKK PNCFELYIPD NKDQVIKACK TEADGRVVEG NHTVYRISAP TPEEKEDWIK CIKAAISRDP FYEMLAARKK KVSSTKRH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.
基因功能參考文獻：
1. Cytohesin-1 is required for Schwann cell migration and that phosphorylation of cytohesin-1 at the Tyr-382 position is important for migration. PMID: 23517829
2. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. PMID: 23012656
3. cytohesin inhibition has an antiproliferative effect in gefitinib-resistant lung cancer cells PMID: 22815959
4. demonstrate an essential role of cytohesin-1/RhoA during ameboid migration in the presence of integrins PMID: 19346499
亞細胞定位：

Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cell junction, tight junction. Cell junction, adherens junction.
組織特異性：

Expressed in colon and small intestine (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: mmu:19157

STRING: 10090.ENSMUSP00000101909

UniGene: Mm.86413