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  4. Recombinant Mouse Collagen type IV alpha-3-binding protein (Col4a3bp)

Recombinant Mouse Collagen type IV alpha-3-binding protein (Col4a3bp)

  • 中文名稱：
    Recombinant Mouse Collagen type IV alpha-3-binding protein(Col4a3bp)
  • 貨號：
    CSB-YP861678MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Collagen type IV alpha-3-binding protein(Col4a3bp)
  • 貨號：
    CSB-EP861678MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Collagen type IV alpha-3-binding protein(Col4a3bp)
  • 貨號：
    CSB-EP861678MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Collagen type IV alpha-3-binding protein(Col4a3bp)
  • 貨號：
    CSB-BP861678MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Collagen type IV alpha-3-binding protein(Col4a3bp)
  • 貨號：
    CSB-MP861678MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Col4a3bp
  • Uniprot No.：
  • 別名：
    Cert1; Cert; Col4a3bp; Stard11; Ceramide transfer protein; CERT; Collagen type IV alpha-3-binding protein; Goodpasture antigen-binding protein; GPBP; START domain-containing protein 11; StARD11; StAR-related lipid transfer protein 11
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-624
  • 氨基酸序列
    MSDNQSWNSS GSEEDPETES GPPVERCGVL SKWTNYIHGW QDRWVVLKNN TLSYYKSEDE TEYGCRGSIC LSKAVITPHD FDECRFDISV NDSVWYLRAQ DPEHRQQWVD AIEQHKTESG YGSESSLRRH GSMVSLVSGA SGYSATSTSS FKKGHSLREK LAEMETFRDI LCRQVDTLQK YFDVCADAVS KDELQRDKVV EDDEDDFPTT RSDGDFLHNT NGNKEKLFPH VTPKGINGID FKGEAITFKA TTAGILATLS HCIELMVKRE ESWQKRHDRE VEKRRRVEEA YKNVMEELKK KPRFGGPDYE EGPNSLINEE EFFDAVEAAL DRQDKIEEQS QSEKVRLHWP TSLPSGDTFS SVGTHRFVQK PYSRSSSMSS IDLVSASDDV HRFSSQVEEM VQNHMNYSLQ DVGGDANWQL VVEEGEMKVY RREVEENGIV LDPLKATHAV KGVTGHEVCN YFWNVDVRND WETTIENFHV VETLADNAII VYQTHKRVWP ASQRDVLYLS AIRKIPALTE NDPETWIVCN FSVDHDSAPL NNRCVRAKIN IAMICQTLVS PPEGDQEISR DNILCKITYV ANVNPGGWAP ASVLRAVAKR EYPKFLKRFT SYVQEKTAGK PILF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
  • 基因功能參考文獻(xiàn)：
    1. Importance of Endoplasmic reticulum to Golgi ceramide traffic to preserve muscle cell insulin signaling, CERT as a major actor in this process. PMID: 29759974
    2. Embryo implantation triggers dynamic spatiotemporal expression of the basement membrane toolkit (Col4a1, GPBP, Lamc1, peroxidasin) during uterine reprogramming. PMID: 27619726
    3. CERT protein deficiency compromises mitochondrial function and leads to senescence in primary cells. PMID: 24642596
    4. knockdown of CERT alone was not sufficient to increase young oocyte's susceptibility to death PMID: 23246342
    5. GPBP directs myofibril formation through interaction with intracellular downstream effector 130-kDa GPBP-interacting protein PMID: 21832087
    6. VEGF inhibitor also partially prevented the stimulation of alpha3(IV) collagen by transforming growth factor (TGF)-beta1. PMID: 15504975
    7. CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus. PMID: 18165232
    8. CERT can attenuate a key metabolic protective mechanism against ceramide-induced apoptosis in keratinocytes PMID: 18411267
    9. CERT is an essential gene for mouse development and embryonic survival and is critical for mitochondrial integrity. PMID: 19139267

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  • 亞細(xì)胞定位：
    Cytoplasm. Golgi apparatus. Endoplasmic reticulum.
  • 數(shù)據(jù)庫鏈接：


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