在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Coagulation factor XI (F11)

  • 中文名稱:
    小鼠F11重組蛋白
  • 貨號:
    CSB-YP007916MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠F11重組蛋白
  • 貨號:
    CSB-EP007916MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠F11重組蛋白
  • 貨號:
    CSB-EP007916MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠F11重組蛋白
  • 貨號:
    CSB-BP007916MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠F11重組蛋白
  • 貨號:
    CSB-MP007916MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    F11Coagulation factor XI; FXI; EC 3.4.21.27; Plasma thromboplastin antecedent; PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    19-389
  • 氨基酸序列
    EC VTKVFKDISF QGGDLSTVFT PSATYCRLVC THHPRCLLFT FMAESSSDDP TKWFACILKD SVTEILPMVN MTGAISGYSF KQCPQQLSTC SKDVYVNLDM KGMNYNSSVV KNARECQERC TDDAHCQFFT YATGYFPSVD HRKMCLLKYT RTGTPTTITK LNGVVSGFSL KSCGLSNLAC IRDIFPNTVL ADLNIDSVVA PDAFVCRRIC THHPTCLFFT FFSQAWPKES QRHLCLLKTS ESGLPSTRIT KSHALSGFSL QHCRHSVPVF CHPSFYNDTD FLGEELDIVD VKGQETCQKT CTNNARCQFF TYYPSHRLCN ERNRRGRCYL KLSSNGSPTR ILHGRGGISG YSLRLCKMDN VCTTKINPR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
  • 基因功能參考文獻:
    1. FXI(-/-) mice have a mild hemostatic defect after injury to the saphenous vein but not after transection of the tail or vessels in the abdominal wall. PMID: 28677246
    2. FXI protects against sepsis derived from Streptococcus pneumoniae or Klebsiella pneumoniae pneumonia at least in part by enhancing the phagocytic capacity of neutrophils by a mechanism that is independent of activation via FXIIa. PMID: 28492700
    3. FXI attenuates part of the allergic response to repeated administration of house dust mite in the airways by a mechanism that is independent of activation via FXII. PMID: 27913422
    4. Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease. PMID: 26817955
    5. FXI deprivation was shown to slow down atherogenesis in Apoe knockout mice. PMID: 26800563
    6. anion-binding sites on FXIa that are required for expression of heparin's cofactor activity during protease inhibition by antithrombin are also required for expression of polyP cofactor activity during FXI activation PMID: 24118982
    7. Factor XI antisense oligonucleotides safely prevent thrombus formation on acutely ruptured atherosclerotic plaques in mice. PMID: 24947525
    8. Studies indicate that targeting factor XI (FXI) by knocking out the gene prevents arterial and vein thrombosis. PMID: 23929304
    9. Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica. PMID: 21724997
    10. fXI and fXII contribute to thrombus formation even when factor VIIa/tissue factor initiates thrombosis. PMID: 20634381
    11. Gene targeting of tissue factor, factor X, and factor VII in mice: their involvement in embryonic development PMID: 11841337
    12. FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse. PMID: 12008966
    13. FIX and FXI deficiency cause similar effects in the carotid artery injury model PMID: 15733058
    14. fXI may have functions in regulation of inflammation or tissue repair distinct from its role in coagulation PMID: 15985536
    15. apolipoprotein E receptor 2 (ApoER2, LRP8), a member of the LDL receptor family, is a platelet receptor for FXI. PMID: 19661487

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Peptidase S1 family, Plasma kallikrein subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 国产交换配乱婬视频| 国产精品尹人在线观看| 免费人成网站视频在线观看| 亚洲人亚洲人成电影网站色| 少妇系列之白嫩人妻| 久爱www成人网免费视频| 亚洲日韩精品无码专区| 日本成aⅴ人片日本伦| 国产伦子系列沙发午睡| 久久免费视频精品在线| 暴力强奷在线播放无码| 麻豆精品久久久久久久99蜜桃| 欧美gv在线观看| 国产亚洲精aa在线观看不卡| av大片在线无码免费| 久久久久人妻一区二区三区| 日韩经典午夜福利发布| 国产av人人夜夜澡人人爽 | 97碰碰碰人妻无码视频| 狠狠色丁香久久婷婷综合图片 | 美女av一区二区三区| 国产无遮挡又黄又爽在线视频| 国产裸体歌舞一区二区| 日韩少妇内射免费播放18禁裸乳| 国产免费毛卡片| 永久黄网站免费视频性色| 巨大乳女人做爰视频在线看| 精品无人国产偷自产在线| 欧美黑人添添高潮a片www| 人人做人人爽人人爱| 成人精品一区日本无码网站| a狠狠久久蜜臀婷色中文网| 亚洲国产成人精品无码区在线观看| 亚洲一区二区三区四区| 国产乱人对白| 激情射精爆插热吻无码视频| 又色又爽又黄又无遮挡的网站 | 久久国产乱子伦精品免费女人| 亚洲人成电影在线天堂色 | 奇米影视第四色首页| 国产suv精品一区二区6|