在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Cleavage and polyadenylation specificity factor subunit 5 (Nudt21)

Recombinant Mouse Cleavage and polyadenylation specificity factor subunit 5 (Nudt21)

  • 中文名稱：
    小鼠Nudt21重組蛋白
  • 貨號：
    CSB-YP861442MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nudt21重組蛋白
  • 貨號：
    CSB-EP861442MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nudt21重組蛋白
  • 貨號：
    CSB-EP861442MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nudt21重組蛋白
  • 貨號：
    CSB-BP861442MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nudt21重組蛋白
  • 貨號：
    CSB-MP861442MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nudt21
  • Uniprot No.：
  • 別名：
    Nudt21; Cpsf5Cleavage and polyadenylation specificity factor subunit 5; Nucleoside diphosphate-linked moiety X motif 21; Nudix motif 21; Nudix hydrolase 21
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-227
  • 氨基酸序列
    SVVPPNRSQ TGWPRGVNQF GNKYIQQTKP LTLERTINLY PLTNYTFGTK EPLYEKDSSV AARFQRMREE FDKIGMRRTV EGVLIVHEHR LPHVLLLQLG TTFFKLPGGE LNPGEDEVEG LKRLMTEILG RQDGVLQDWV IDDCIGNWWR PNFEPPQYPY IPAHITKPKE HKKLFLVQLQ EKALFAVPKN YKLVAAPLFE LYDNAPGYGP IISSLPQLLS RFNFIYN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7. Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function(PubMed:29249356). Binds to chromatin. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides.
  • 基因功能參考文獻：
    1. Pre-messenger RNA cleavage factor I (CFIm): potential role in alternative polyadenylation during spermatogenesis. PMID: 18032416
    2. Here we report that the CFIm subunits NUDT21/CPSF5 and CPSF6 are highly enriched in mouse male germ cells relative to somatic cells. PMID: 18032416
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Nudix hydrolase family, CPSF5 subfamily
  • 組織特異性：
    Expressed in testis. Expressed in male germ cells (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美日韩一区二区成人午夜电影| 国产精品成人一区二区三区| 极品尤物一区二区三区| 在线观看欧美一区二区三区| www激情内射在线看| 男女做爰无遮挡性视频| 亚洲成a人片在线观看无码专区| 久久天天躁狠狠躁夜夜av | 成熟女人毛片www免费版在线| 成av人片在线观看www| 99视频精品全部免费免费观看| 99精品国产福久久久久久| 18禁高潮出水呻吟娇喘蜜芽| 日韩精品av一区二区三区| 亚洲最大av无码国产| 亚洲日韩精品射精日| 在线播放亚洲人成电影| 亚洲精品无码国产片| 亚洲午夜性猛春交xxxx| 国产a线视频播放| 久久人人做人人妻人人玩精品va| 亚洲欧美中文日韩v在线观看| 亚洲无线看天堂av| 亚洲va中文字幕无码久久不卡| 亚洲女人被黑人巨大进入| 精品国产偷窥一区二区| 亚洲人成电影网站色| 无码专区亚洲制服丝袜| 国产人妻人伦精品1国产盗摄| 国产伦精品一区二区三区| 日韩亚洲中字无码一区二区三区 | 亚洲乱码中文字幕在线| 成人性三级欧美在线观看| 国产成人精品免费午夜app| 抽插丰满内射高潮视频| 玩弄漂亮少妇高潮白浆| 国产肉丝袜在线观看| 人妻无码第一区二区三区| 无码少妇精品一区二区免费动态 | 俄罗斯老熟妇色xxxx| 女被男啪到哭的视频网站|