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  4. Recombinant Mouse Cell division cycle-associated protein 7 (Cdca7)

Recombinant Mouse Cell division cycle-associated protein 7 (Cdca7)

  • 中文名稱：
    Recombinant Mouse Cell division cycle-associated protein 7(Cdca7)
  • 貨號：
    CSB-YP861510MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cell division cycle-associated protein 7(Cdca7)
  • 貨號：
    CSB-EP861510MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cell division cycle-associated protein 7(Cdca7)
  • 貨號：
    CSB-EP861510MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Cell division cycle-associated protein 7(Cdca7)
  • 貨號：
    CSB-BP861510MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cell division cycle-associated protein 7(Cdca7)
  • 貨號：
    CSB-MP861510MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Cdca7
  • Uniprot No.：
  • 別名：
    Cdca7; Cell division cycle-associated protein 7
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-382
  • 氨基酸序列
    MEARRARQKA LKVKNLKDVR YMKLISMETS SSSDDSCDSF ASDNFANTRL QLNREGCRTR SQCRHSGPLR VAMKFPARNT RRAASKKAAP PKPSESSAND SHSDSEEEEE EEEEEDGMNF LEKRALNIKQ NKAMLAKLMS ELESFPGLFS GRHSLPGHRA KDSKSPRRRT FPGVATRRNP ERRTRPLTRS RSRILGSLGA LPTEEEEEEE EEEEDKYMLV RQRKSMDSYM NDDDVPRSRR PGSMTLPHII RPVEEVTEEE IRNICSNSRE KIYNRSLGST CHQCRQKTTD TKTNCRNPDC WGIRGQFCGP CLRNRYGEEV KDALLDPNWH CPPCRGICNC SFCRQRDGRC ATGVLVYLAK YHGFGNVHAY LKSLKQEFEM QA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
  • 基因功能參考文獻：
    1. Pax6 normally represses Cdca7 expression in the lateral cortex and that repression of Cdca7 in cells of this region is required for their production of a normal complement of Tbr2-expressing intermediate progenitors PMID: 28583079
    2. Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations PMID: 27466202
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數據庫鏈接：


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