在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Cathepsin G (Ctsg)

In Stock
  • 中文名稱:
    Recombinant Mouse Cathepsin G(Ctsg)
  • 貨號:
    CSB-EP006190MO
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006190MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Ctsg.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006190MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Ctsg.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ctsg; Cathepsin G; EC 3.4.21.20; Vimentin-specific protease; VSP
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    42.9kDa
  • 表達(dá)區(qū)域:
    21-261aa
  • 氨基酸序列
    IIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Cleaves vimentin. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa.
  • 基因功能參考文獻(xiàn):
    1. these findings present evidence of an arterial-specific recruitment pattern centered on CatG-instructed adhesion strengthening. The inhibition of this process could provide a novel strategy for treatment of arterial inflammation with limited side effects. PMID: 27660294
    2. Cathepsin G activity may impair efferocytosis, which could lead to an accumulation of lesion-associated apoptotic cells and the accelerated progression of early atherosclerotic lesions to more complex lesions in Apoe(-/-) mice. PMID: 23934850
    3. SerpinB1 is critical for maintaining polymorphonuclear neutrophils survival by antagonizing intracellular cathepsin G activity. PMID: 23532733
    4. Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions. PMID: 22879591
    5. Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice. PMID: 22461690
    6. This is the first study showing a contribution of neutrophil-derived neutral serine proteases CG and NE to lung-protective immunity against focal pneumonia-inducing serotype 19 S. pneumoniae in mice. PMID: 21911460
    7. In the absence of a pathogen challenge, neutrophil-derived proteases and nucleosomes contribute to large vessels thrombosis, the main trigger of myocardial infarction and stroke. PMID: 20676107
    8. Inhibition of TGF-beta significantly reduces microvessel density in mammary tumor-induced bone lesions, mediated by decreased expression of both vascular endothelial growth factor (VEGF) and monocyte chemotactic protein (MCP)-1. PMID: 19646811
    9. neutrophil elastase and cathepsin G are inhibited by PAI-1 mutants PMID: 15131125
    10. cathepsin G activity at the tumor-bone interface plays an important role in mammary tumor-induced osteolysis through RANKL PMID: 18632634
    11. both Cat-G and PAR(4) play key roles in generating and/or amplifying relapses in ulcerative colitis PMID: 19528350
    12. Cathepsin G and MMP9 were identified as proteases involved in enhanced TGF-beta signaling at the tumor-bone interface of mammary tumor-induced osteolytic lesions. PMID: 19671689
    13. Serine protease required for resistance to microbial infection; contributes to pathogenessis in endotoxic shock PMID: 10714686

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell surface. Membrane; Peripheral membrane protein.
  • 蛋白家族:
    Peptidase S1 family
  • 組織特異性:
    In adult, detected only in bone marrow where expression is restricted to a small population of early myeloid cells.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 丁香婷婷综合久久来来去| 无翼乌工口全彩肉肉无遮挡18 | 韩国的无码av看免费大片在线| 中文字幕在线不卡精品视频99| av无码人妻中文字幕| 在线精品无码字幕无码av| av永久天堂一区二区三区| 国产999精品久久久久久| www.-级毛片线天内射视视| 国产精品一区二区香蕉| 日韩制服国产精品一区| 精品一区二区三区在线播放视频| 色老头在线一区二区三区| 97碰碰碰人妻无码视频| 黄网站欧美内射| 亚洲 日韩 国产 中文有码| 国产精品jk白丝在线播放| 日韩一区二区三免费高清| 天天躁夜夜躁狠狠是什么心态| 亚洲爆乳无码精品aaa片蜜桃| 99久久综合狠狠综合久久| 亚洲系列一区中文字幕| 国产婷婷丁香五月缴情成人网| 精品人妻无码一区二区三区蜜桃一| 成人无码免费一区二区三区| 无码人妻丰满熟妇区毛片 | 99久久国产亚洲高清观看| 亚洲一区二区三区国产精品无码| 国产又色又爽又高潮免费| 国产色无码精品视频国产| 国产一区二区三区在线蜜桃| 97色成人综合网站| 亚洲 熟女 久久 国产| 午夜三级a三级三点窝| 国产男女免费完整视频| 中国人妻被两个老外三p| 东京热人妻丝袜av无码| 精品国产亚洲一区二区三区| 亚洲国产精品特色大片观看完整版| 国内外精品激情刺激在线| 国产精品va在线观看h|