在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Cathepsin G (Ctsg)

In Stock
  • 中文名稱:
    Recombinant Mouse Cathepsin G(Ctsg)
  • 貨號:
    CSB-EP006190MO
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006190MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Ctsg.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006190MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Ctsg.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ctsg; Cathepsin G; EC 3.4.21.20; Vimentin-specific protease; VSP
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    42.9kDa
  • 表達(dá)區(qū)域:
    21-261aa
  • 氨基酸序列
    IIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Cleaves vimentin. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa.
  • 基因功能參考文獻(xiàn):
    1. these findings present evidence of an arterial-specific recruitment pattern centered on CatG-instructed adhesion strengthening. The inhibition of this process could provide a novel strategy for treatment of arterial inflammation with limited side effects. PMID: 27660294
    2. Cathepsin G activity may impair efferocytosis, which could lead to an accumulation of lesion-associated apoptotic cells and the accelerated progression of early atherosclerotic lesions to more complex lesions in Apoe(-/-) mice. PMID: 23934850
    3. SerpinB1 is critical for maintaining polymorphonuclear neutrophils survival by antagonizing intracellular cathepsin G activity. PMID: 23532733
    4. Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions. PMID: 22879591
    5. Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice. PMID: 22461690
    6. This is the first study showing a contribution of neutrophil-derived neutral serine proteases CG and NE to lung-protective immunity against focal pneumonia-inducing serotype 19 S. pneumoniae in mice. PMID: 21911460
    7. In the absence of a pathogen challenge, neutrophil-derived proteases and nucleosomes contribute to large vessels thrombosis, the main trigger of myocardial infarction and stroke. PMID: 20676107
    8. Inhibition of TGF-beta significantly reduces microvessel density in mammary tumor-induced bone lesions, mediated by decreased expression of both vascular endothelial growth factor (VEGF) and monocyte chemotactic protein (MCP)-1. PMID: 19646811
    9. neutrophil elastase and cathepsin G are inhibited by PAI-1 mutants PMID: 15131125
    10. cathepsin G activity at the tumor-bone interface plays an important role in mammary tumor-induced osteolysis through RANKL PMID: 18632634
    11. both Cat-G and PAR(4) play key roles in generating and/or amplifying relapses in ulcerative colitis PMID: 19528350
    12. Cathepsin G and MMP9 were identified as proteases involved in enhanced TGF-beta signaling at the tumor-bone interface of mammary tumor-induced osteolytic lesions. PMID: 19671689
    13. Serine protease required for resistance to microbial infection; contributes to pathogenessis in endotoxic shock PMID: 10714686

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell surface. Membrane; Peripheral membrane protein.
  • 蛋白家族:
    Peptidase S1 family
  • 組織特異性:
    In adult, detected only in bone marrow where expression is restricted to a small population of early myeloid cells.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 精品三级av无码一区| 亚洲国产另类久久久精品| 伊伊人成亚洲综合人网7777| 西西人体444www大胆无码视频| 亚洲精品一区二区三区麻豆| 四虎永久在线精品免费观看| 无码爆乳护士让我爽| 中文字幕无线码| 国产精品一区二区av蜜芽| 东京一本一道一二三区| 中文字幕人妻熟女人妻| 久久综合九色欧美综合狠狠| 色噜噜狠狠色综合日日| 日韩在线永久免费播放| 无码福利在线观看1000集| 制服丝袜另类专区制服| 久久无码专区国产精品s| 女乱高潮久久久久久爽爽| 国产亚洲精品久久久999蜜臀| 国精产品一区一区三区mba下载| 无码无遮挡又大又爽又黄的视频 | 国内精品久久久久影院亚瑟| 欧美xxxxx高潮喷水| 国产99久久久国产精品免费看| 日本一区二区无卡高清视频| 欧美18videosex性欧美黑吊| 国产亚洲精品久久久网站好莱| 国产成人啪精品视频免费网站软件| av无码久久久久不卡网站下载| 丰满人妻翻云覆雨呻吟视频| 日本免费人成视频播放| 2020年无码国产精品高清免费| 国产成人精品av| 69久久精品无码一区二区| 香蕉噜噜噜噜私人影院| 亚洲视频日韩视欧美视频| 性做久久久久久| 国产一区丝袜在线播放| 精品无码国模私拍视频| 亚洲va国产va天堂va久久| 亚洲中文字幕日产无码成人片|