在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse CDK5 and ABL1 enzyme substrate 1 (Cables1)

Recombinant Mouse CDK5 and ABL1 enzyme substrate 1 (Cables1)

  • 中文名稱：
    Recombinant Mouse CDK5 and ABL1 enzyme substrate 1(Cables1)
  • 貨號：
    CSB-YP884155MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse CDK5 and ABL1 enzyme substrate 1(Cables1)
  • 貨號：
    CSB-EP884155MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse CDK5 and ABL1 enzyme substrate 1(Cables1)
  • 貨號：
    CSB-EP884155MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse CDK5 and ABL1 enzyme substrate 1(Cables1)
  • 貨號：
    CSB-BP884155MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse CDK5 and ABL1 enzyme substrate 1(Cables1)
  • 貨號：
    CSB-MP884155MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Cables1
  • Uniprot No.：
  • 別名：
    Cables1; CablesCDK5 and ABL1 enzyme substrate 1; Interactor with CDK3 1; Ik3-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-568
  • 氨基酸序列
    MAAATATAGT AACSSSSSSR GGSTDAAATS GVQPPPPPPA TAPPEPLRKP RMDPRRRQAA LSFLTNISLD GRPPLQDHEW GGGEEGGGTK PGARARLSLL AAGCNAFSAP GTAAAPWTAG SGSSPCPLPP SLVPRVLGEP SQPPRSAPAV TGAQLQLPDG PGGAGQEELE EDDAFTNVQV PSASFLGSGT PGSTSGSRGR LNSFTQGILP IAFSRQNSQN YCALEQSGQG GSTSALEQLQ RSRRRLISQR SSLETLEDIE ENAPLRRCRT LSGSPRPKNF KKIHFIKNMR QHDTKNGRDL KLDGGRQSAG AMSLKEIIGL EGVELGADGK TVSYTQFLLP TNAFGNRRNT IDSTASFSQF RSLSHRSLSM GRAGSTQGSL DAGSDLGDFM DYDPNLLDDP QWPCGKHKRV LTFPSYMTTV IDYVKPSDLK KDMNETFKEK FPHIKLTLSK IRSLKREMRK LAQEDCGFEE PTVAMAFVYF EKLALRGKLN KQNRKLCAGA CVLLAAKVGS DLRKHEVKHL IDKLEEKFRL NRRELIAFEF PVLVALEFAL HLPEHEVMPH YRRLIQSS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.
  • 基因功能參考文獻：
    1. Loss of Cables1 enhances tumor progression in the Apc(Min/+) mouse model and activates the Wnt/beta-catenin signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model. PMID: 23792637
    2. Agenesis of the corpus callosum frequency in Cables1(+/TAS) mice was significantly lower than that in Cables1(-/TAS) mice, indicating that wild-type Cables1 interfered with the dominant negative effect of Cables1(TAS). PMID: 24336072
    3. Cables may be involved in the pathogenesis of ovarian carcinomas PMID: 13679449
    4. Loss or suppression of Cables may be an early step in the development of endometrial cancer. PMID: 14729625
    5. Cables is a relevant target of the chromosome 18q deletions frequently seen in human colorectal cancer. PMID: 16210915
    6. Cables1 null mice exhibit a significant expansion of oocyte numbers at the expense of oocyte quality throughout adulthood. PMID: 17912041

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm. Cell projection, growth cone. Note=Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons.
  • 蛋白家族：
    Cyclin family
  • 組織特異性：
    Ubiquitous. Expressed in postnatal day 1 (P1), in postmitotic neurons of the subplate, cortex (V/VI) and marginal zone; in postnatal day 7 (P7), in all layers of the cerebral cortex and in the CA1 and CA2 regions of the hippocampus (at protein level). Hig
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲国产精品久久网午夜 | 真人与拘做受免费视频一| 又粗又大内射免费视频小说| 夜夜躁狠狠躁2021| 亚洲经典国产精华液单品榜| 日本一二免费不卡区| 欧美精品九九久久久久久久久 | 中文字幕日本六区小电影| 欧美成人精品a∨在线观看| 一区二区三区鲁丝不卡麻豆| 亚洲国产成人第一天堂| 国产精品麻豆欧美日韩ww| 久久久欧美国产精品人妻噜噜| 蜜臀久久99精品久久久久久做爰| 影视av久久久噜噜噜噜噜三级| 把插八插露脸对白内射| 国产精品亚洲lv粉色| 久久久精品2020免费观看| 日本一卡2卡3卡4卡免费精品| 国产 | 欧洲野花视频天堂视频p| 国产精品国产亚洲精品看不卡| 精品产区wnw2544| 四虎一区二区成人免费影院网址| 国产精品禁忌a片特黄a片| 中文字幕日韩一区二区不卡| 久久亚洲春色中文字幕久久久| 六月丁香婷婷色狠狠久久| av激情亚洲男人的天堂| 欧美 日韩 亚洲 精品二区| 色婷婷综合中文久久一本| 亚洲欧洲日产国码在线| 亚洲国产一成人久久精品| 午夜少妇性影院私人影院在线| 国产亚洲精品久久久久久久久动漫| 色情无码一区二区三区| 亚洲一卡一卡二新区迎热烈讨论| 国产内射爽爽大片| 最大胆裸体人体牲交| 亚洲国内精品自在线影院| 在线精品国产大象香蕉网| 狂野欧美激情性xxxx|