在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse CD180 antigen (Cd180), partial

Recombinant Mouse CD180 antigen (Cd180), partial

  • 中文名稱：
    Recombinant Mouse CD180 antigen(Cd180),partial
  • 貨號：
    CSB-YP714013MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse CD180 antigen(Cd180),partial
  • 貨號：
    CSB-EP714013MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse CD180 antigen(Cd180),partial
  • 貨號：
    CSB-EP714013MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse CD180 antigen(Cd180),partial
  • 貨號：
    CSB-BP714013MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse CD180 antigen(Cd180),partial
  • 貨號：
    CSB-MP714013MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cd180; Ly78; Rp105; CD180 antigen; Lymphocyte antigen 78; Ly-78; Radioprotective 105 kDa protein; CD antigen CD180
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
  • 基因功能參考文獻：
    1. Silencing Cd180 results in increased phagocytosis while tempering the production of the proinflammatory cytokine TNF during Borrelia burgdorferi infection. PMID: 29511161
    2. the close association between the increased proportion of CD180-negative B cells and the activation of IFN-alpha signaling in Systemic lupus erythematosus, is reported. PMID: 26277892
    3. Data show that RP105 knockout (-/-) smooth muscle cells and mast cells secreted higher levels of chemokine (C-C motif) ligand 2 protein (CCL2). PMID: 27053419
    4. These data unveil a novel innate immune signaling axis that orchestrates key cytokine responses of macrophages and provide molecular insight into the functions of RP105 as an innate immune receptor for mycobacteria. PMID: 26371254
    5. RP105 regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model. PMID: 24945347
    6. RP105 deficiency results in reduced early atherosclerotic plaque development with a marked decrease in lesional macrophage content, which may be due to disturbed migration of RP105 deficient monocytes resulting from CCR2 downregulation PMID: 25484103
    7. Deficiency of the endogenous TLR4 inhibitor, RP105, leads to pronounced cardiac dilation after myocardial infarction. PMID: 25156852
    8. Data indicate that RP105 and TLR4 are both expressed by vascular smooth muscle cells (VSMC). PMID: 23844130
    9. RP105 deficiency on circulating cells results in an intriguing unexpected TLR-associated mechanisms that decrease atherosclerotic lesion formation with alterations on proinflammatory B2 B cells. PMID: 24115036
    10. The function of TLR2 and TLR4 in response to TLR ligands could be associated with each other by RP105. PMID: 23483427
    11. Data show that both RP105/MD-1 and TLR4/MD-2 are expressed in marginal zone (MZ) B cells. PMID: 22354914
    12. The RP105/MD-1 complex is a major mediator of adipose tissue inflammation independent of TLR4 signaling and may represent a novel therapeutic target for obesity-associated metabolic disorders. PMID: 22396206
    13. Modulation of B cell proliferation by RP105 is not a function of B cell-intrinsic expression of RP105. PMID: 22291190
    14. Both mouse and human RP105/MD-1 exhibit dimerization of the 1:1 RP105/MD-1 complex, demonstrating a novel organization. PMID: 21959264
    15. CD180 stimulation induces intrinsic B cell proliferation and differentiation PMID: 21918197
    16. RP105 regulated TLR4 signaling in dendritic cells PMID: 15852007
    17. A signal via RP105 is uniquely important for regulating Toll-like receptor-dependent antibody production to microbial membranes. PMID: 15905547
    18. RP105 regulates the antigen-presenting cell function and Treg development, which induced the attenuation of the cell-mediated immune responses and, as a result, suppressed the development of collagen-induced arthritis . PMID: 18847495
    19. The data identify RP105 as an accessory molecule for TLR2, forming part of the receptor complex for innate immune recognition of mycobacterial lipoproteins. PMID: 19154986

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Toll-like receptor family
  • 組織特異性：
    B-lymphocytes and spleen. Not detected in thymus, kidney, muscle, heart, brain or liver.
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美精品一区二区黄a片| 国产亚洲欧洲日韩在线...| 各处沟厕大尺度偷拍女厕嘘嘘| 亚洲精品国产成人一区二区| 中国少妇内射xxxhd| 蜜桃麻豆www久久国产sex| 99久久伊人精品综合观看| 成在线人视频免费视频| 国产精品无码一区二区桃花视频| 亚洲香蕉网久久综合影视| 一本加勒比hezyo中文无码| 亚洲а∨精品天堂在线| 日日碰狠狠躁久久躁综合小说| 日本少妇裸体做爰高潮片| 亚洲中文色欧另类欧美| 日日碰狠狠添天天爽超碰97| 欧美综合天天夜夜久久| 熟妇丰满多毛的大隂户| 日本一道综合久久aⅴ免费| 日本一本一区二区免费播放| 啦啦啦www在线观看免费视频 | 欧美精品免费观看二区| 性猛交ⅹxxx富婆视频| 毛片tv网站无套内射tv网站| 亚洲中文字幕久久精品无码va| 男女做爰无遮挡性视频| 午夜亚洲福利在线老司机| 黑人大战亚洲人精品一区| 国产精品久久香蕉免费播放| 国产激情高中生呻吟视频 | 亚洲精品国产第一综合99久久| av片在线观看免费| 亚洲高清成人aⅴ片| 69久久精品无码一区二区无码 | 2019最新中文字幕在线观看| 国产精品99久久精品爆乳| 中文人妻av久久人妻水密桃 | 波多野结衣的av一区二区三区| 亚洲精品无码高潮喷水a片软| 色诱久久久久综合网ywww| 国产乱子伦视频一区二区三区 |