在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse C-type mannose receptor 2 (Mrc2), partial

Recombinant Mouse C-type mannose receptor 2 (Mrc2), partial

  • 中文名稱：
    小鼠Mrc2重組蛋白
  • 貨號：
    CSB-YP731055MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mrc2重組蛋白
  • 貨號：
    CSB-EP731055MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mrc2重組蛋白
  • 貨號：
    CSB-EP731055MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mrc2重組蛋白
  • 貨號：
    CSB-BP731055MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mrc2重組蛋白
  • 貨號：
    CSB-MP731055MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Mrc2; Kiaa0709; C-type mannose receptor 2; Lectin lambda; Macrophage mannose receptor 2; CD antigen CD280
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
  • 基因功能參考文獻：
    1. Findings show that under in vivo conditions, uPARAP does not play a role in the phagocytic uptake of collagen fibrils by fibroblasts. PMID: 27922193
    2. Our findings identify sarcoma cell-resident uPARAP/Endo180 as a central player in the bone degeneration of advanced osteosarcoma PMID: 26466547
    3. AGE-dependent modification of the basal lamina induces invasive behaviour in non-transformed prostate epithelial cells via Endo180 pathway linked to cancer progression. PMID: 25408555
    4. uPARAP function in cutaneous wound repair PMID: 24663959
    5. Genetic ablation of the Mrc2 impaired the intracellular collagen degradation pathway. PMID: 24019537
    6. This function of uPARAP/Endo180 defines a novel role of intracellular collagen turnover in fibrosis protection. PMID: 22294280
    7. uPARAP is highly expressed in the murine lung, and loss of uPARAP leads to differences in lung mechanics, lung permeability, and collagen content after injury PMID: 21940816
    8. data establish an important fibrosis-attenuating role for Mrc2-expressing renal interstitial cells and suggest the involvement of a lysosomal collagen turnover pathway PMID: 22095946
    9. A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180. PMID: 21768090
    10. targeted deletion of Endo180 exons 2-6 results in cells that have a defect in collagen binding and internalization and an impaired migratory phenotype PMID: 12835757
    11. Deletion of uPARAP/Endo180 impaired collagen turnover critical to tumor expansion, as evidenced by abrogation of collagen uptake, tumor fibrosis, and blunted tumor growth. uPARAP/Endo180 mediates collagen turnover in a pathophysiological context. PMID: 15967816
    12. The mannose receptor is the main candidate for being the endocytic denatured collagen receptor on liver sinusoidal endothelial cells PMID: 17518370
    13. fibroblast-mediated collagen degradation proceeds preferentially as a sequential mechanism in which extracellular collagenolysis is followed by uPARAP/Endo180-mediated endocytosis of large collagen fragments. PMID: 17623673
    14. we demonstrate extensive uPARAP expression in the mesenchyme throughout murine lung development. PMID: 18639653

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Highly expressed in heart, lung and kidney, but little or no expression in brain, thymus or adult liver. Expressed at highly endothelialized sites such as those in choroid plexus and kidney glomerulai as well as in chondrocytes in cartilaginous regions of
  • 數據庫鏈接：


主站蜘蛛池模板： 国产成人精品三级麻豆| 精品少妇无码av无码专区| 99久久久无码国产精品6| 18禁美女黄网站色大片免费看| 国内自产少妇自拍区免费| 久久影院九九被窝爽爽| 久青草无码视频在线观看| 久久久这里只有精品10| 中文字幕无线观看不卡网站| 亚洲另类激情专区小说| 少妇粗大进出白浆嘿嘿视频| 国产精品igao视频| 国产私拍大尺度在线视频| 啊轻点内射在线视频| 国产美女露脸口爆吞精| 日本免费高清一本视频| 久久精品国产清自在天天线| 亚洲熟妇国产熟妇肥婆| 亚洲一卡一卡二新区无人区| 国产在线无码不卡影视影院| 亚洲国产精品自在拍在线播放蜜臀| 成 人 网 站 免费观看| 一个人看的www视频免费观看 | 欧洲lv尺码大精品久久久| 无套内射在线无码播放| 久久99国产精一区二区三区| 日韩精品人妻系列一区二区三区 | 激情综合色综合啪啪五月丁香| 亚洲一卡2卡3卡4卡 精品| 久久精品国产99精品亚洲| 亚洲欧洲美洲在线观看| 人人超人人超碰超国产97超碰| 免费观看18禁无遮挡真人网站 | 狠狠色综合网站久久久久久久| 国产一区二区三区精品av| 九九久久精品国产波多野结衣| 特黄熟妇丰满人妻无码| 精品夜夜爽欧美毛片视频| 久久综合色一综合色88| 亚洲人成小说网站色| 亚洲色丰满少妇高潮18p|