在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2 (Baiap2)

Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2 (Baiap2)

  • 中文名稱：
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2(Baiap2)
  • 貨號：
    CSB-YP805295MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2(Baiap2)
  • 貨號：
    CSB-EP805295MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2(Baiap2)
  • 貨號：
    CSB-EP805295MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2(Baiap2)
  • 貨號：
    CSB-BP805295MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1-associated protein 2(Baiap2)
  • 貨號：
    CSB-MP805295MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Baiap2Brain-specific angiogenesis inhibitor 1-associated protein 2; BAI-associated protein 2; BAI1-associated protein 2; Insulin receptor substrate protein of 53 kDa; IRSp53; Insulin receptor substrate p53; Insulin receptor tyrosine kinase 53 kDa substrate
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-535
  • 氨基酸序列
    MSLSRSEEMH RLTENVYKTI MEQFNPSLRN FIAMGKNYEK ALAGVTFAAK GYFDALVKMG ELASESQGSK ELGDVLFQMA EVHRQIQNQL EETLKSFHNE LLTQLEQKVE LDSRYLSAAL KKYQTEQRSK GDALDKCQAE LKKLRKKSQG SKNPQKYSDK ELQYIDAISN KQGELENYVS DGYKTALTEE RRRFCFLVEK QCAVAKNSAA YHSKGKELLA QKLPLWQQAC ADPNKIPDRA VQLMQQMANS NGSILPSALS ASKSNLVISD PIPGAKPLPV PPELAPFVGR MSAQENVPVM NGVAGPDSED YNPWADRKAA QPKSLSPPQS QSKLSDSYSN TLPVRKSVTP KNSYATTENK TLPRSSSMAA GLERNGRMRV KAIFSHAAGD NSTLLSFKEG DLITLLVPEA RDGWHYGESE KTKMRGWFPF SYTRVLDSDG SDRLHMSLQQ GKSSSTGNLL DKDDLALPPP DYGTSSRAFP TQTAGTFKQR PYSVAVPAFS QGLDDYGARS VSRNPFANVH LKPTVTNDRS APLLS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
  • 基因功能參考文獻：
    1. double knockout of IRSp53 and its closest family member, IRTKS, resulted in exacerbated placental abnormalities, particularly in spongiotrophoblast differentiation and development, giving rise to complete embryonic lethality. PMID: 28067313
    2. CDC42 activation inhibits this activity and promotes IRSp53-dependent recruitment and clustering of VASP to drive actin assembly. PMID: 24076653
    3. VASP physically interacted with IRSp53 in NIH-Src cells and was essential for podosome formation. PMID: 23555988
    4. propose that IRSp53 is a negative regulator of myogenic differentiation which correlates with the observed down regulation of IRSp53 expression during myoblast differentiation to myotubes PMID: 22465711
    5. mDia1 and WAVE2 are important Src homology 3 domain partners of IRSp53 in forming filopodia. PMID: 22179776
    6. IRSp53, through its interaction with Eps8, not only affects cell migration but also dictates cellular growth in cancer cells. PMID: 20418908
    7. IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 PMID: 20360004
    8. In cells spread well on a laminin substrate, IRSp53 was localised at the tips of both lamellipodia and filopodia and in in living cells during protrusion. PMID: 12734400
    9. Rac1, along with IRSp53 and Abi1, is involved in a more complex and tight regulation of WAVE2 than one operating solely through membrane localization. PMID: 18198193
    10. Consistent with altered synaptic plasticity, IRSp53-deficient mice exhibit cognitive deficits in the contextual fear-conditioning paradigm PMID: 19208628
    11. Formation of filopodia is dependent on the Rho family GTPase Cdc42 and the Cdc42 effector IRSp53 (Baiap2). PMID: 19820184

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Cytoplasm, cytoskeleton.
  • 組織特異性：
    Detected in liver, brain, olfactory bulb, brain cortex, caudate putamen, hypothalamus and cerebellum.
  • 數據庫鏈接：


主站蜘蛛池模板： 内射国产内射夫妻免费频道| 天天躁夜夜躁狠狠躁2021a2| 人妻中出受孕 中文字幕在线| 国产色无码精品视频国产| 精品玖玖玖视频在线观看| 夜夜添无码试看一区二区三区| 97se亚洲精品一区二区| 国产成人精品无码免费看| 国产精品人妻一码二码尿失禁| 无码精品a∨在线观看无广告| 精品无码久久久久国产电影| 久久av无码精品人妻系列试探| 髙清国产性猛交xxxand| 一本一道波多野结衣一区| 亚洲中文字慕日产2021| 欧美丰满熟妇bbb久久久| 又紧又大又爽精品一区二区| 色综合色狠狠天天综合网| 亚洲精品久久久久午夜aⅴ| 中文字幕精品久久久久人妻红杏1 久久久精品日本一区二区三区 | 久久aⅴ无码av高潮av喷吹| 日本毛茸茸的丰满熟妇| 国产又粗又硬又大爽黄老大爷| 蜜臀av在线播放一区二区三区| 少妇的肉体k8经典| 亚洲欧美v国产一区二区| 国产精品日本一区二区不卡视频| 日日噜噜噜夜夜爽爽狠狠视频| 国产情侣真实54分钟在线| 日韩国产亚洲一区二区三区| 曰批视频免费30分钟成人| 女厕偷窥一区二区三区| 忍着娇喘人妻被中出中文字幕| 中文人妻无码一区二区三区在线| 国精产品一区一区三区| 国产精品美女久久久久久| 国产午夜福利院757视频| 四虎www成人影院观看| 亚洲婷婷五月综合狠狠爱| 欧美村妇激情内射| 伊人久久综合无码成人网|