在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Brain-specific angiogenesis inhibitor 1 (Bai1), partial

  • 中文名稱:
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1(Bai1) ,partial
  • 貨號:
    CSB-YP002541MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1(Bai1) ,partial
  • 貨號:
    CSB-EP002541MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1(Bai1) ,partial
  • 貨號:
    CSB-EP002541MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1(Bai1) ,partial
  • 貨號:
    CSB-BP002541MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse Brain-specific angiogenesis inhibitor 1(Bai1) ,partial
  • 貨號:
    CSB-MP002541MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Adgrb1; Bai1Adhesion G protein-coupled receptor B1; Brain-specific angiogenesis inhibitor 1) [Cleaved into: Vasculostatin-120; Vstat120); Vasculostatin-40; Vstat-40)]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion. Activates the Rho pathway in a G-protein-dependent manner. Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity. Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1. Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma.; Inhibits angiogenesis in a CD36-dependent manner.; Inhibits angiogenesis.
  • 基因功能參考文獻:
    1. these findings suggest that BAI1 mediates the clearance of Gram-negative bacteria by stimulating both phagocytosis and NADPH oxidase activation, thereby coupling bacterial detection to the cellular microbicidal machinery. PMID: 26838550
    2. transgenic mice overexpressing BAI1 had fewer apoptotic cells, reduced inflammation, and attenuated disease. Boosting BAI1-mediated uptake by intestinal epithelial cells was important in attenuating inflammation. PMID: 27037190
    3. BAI1(-) mice have deficits in hippocampus-dependent spatial learning and memory, enhanced long-term potentiation, impaired long-term depression, and postsynaptic density thinning. BAI1 stops PSD-95 polyubiquitination/degradation via interaction with MDM2. PMID: 25751059
    4. data identify apoptotic cells as a new type of cue that induces signalling via the phosphatidylserine receptor BAI1 to promote fusion of healthy myoblasts, with important implications for muscle development and repair PMID: 23615608
    5. expression pattern in brain regions and role as anti-angiogenic factor in mature neuropil PMID: 20888903
    6. findings identify BAI1 as a pattern recognition receptor that mediates nonopsonic phagocytosis of Gram-negative bacteria by macrophages and directly affects the host response to infection PMID: 21245295
    7. BAI1 is a phosphatidylserine recognition receptor that can directly recruit a Rac-GEF complex to mediate the uptake of apoptotic cells. PMID: 17960134

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, phagocytic cup. Cell junction, focal adhesion. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density.; [Vasculostatin-120]: Secreted.; [Vasculostatin-40]: Secreted.
  • 蛋白家族:
    G-protein coupled receptor 2 family, LN-TM7 subfamily
  • 組織特異性:
    In brain, widespread expression in all neuropil-rich zones including spinal cord gray matter, cerebellar molecular layer, cerebral cortex, thalamic nuclei and basal ganglia with no expression in white matter (at protein level). In the cerebellar molecular
  • 數據庫鏈接:


主站蜘蛛池模板: 成年女人a毛片免费视频| 熟女熟妇伦av网站| 亚洲高清无在码在线电影不卡 | 久久久成人毛片无码| 一个人看的www视频免费观看| 熟女人妻一区二区三区免费看 | 久久精品aⅴ无码中文字字幕蜜桃| 午夜不卡久久精品无码免费| 人妻丰满熟妇av无码区hd| 天无日天天射天天视| 亚洲综合另类小说色区色噜噜| 日日噜噜夜夜狠狠va视频| 99久久免费国产精精品| 在线播放亚洲第一字幕| yyyy11111少妇无码影院| 少妇人妻大乳在线视频不卡| 欧美亚洲日本日韩在线| 欧美xxxx做受欧美88| 艳妇臀荡乳欲伦交换h在线观看| 中文字幕av无码不卡| 大香线蕉伊人超碰| 国产亚洲精品自在久久vr| 久久国产成人精品av| а√天堂www在线天堂小说| 在线中文新版最新版在线| 成人免费毛片内射美女app| 久久九九国产精品怡红院| 国产二级一片内射视频插放| 亚洲人成人网站色www| 午夜福利视频极品国产83| 任我爽橹在线精品视频| 东京热无码av男人的天堂| 久久婷婷五月综合色国产香蕉 | 国产区图片区小说区亚洲区| 久天啪天天久久99久久| 日韩午夜理论片 中文字幕| 国产成人涩涩涩视频在线观看| 日本最新免费二区三区| 忍着娇喘人妻被中出中文字幕 | 华人少妇被黑人粗大的猛烈进| 欧美mv日韩mv国产网站app|