在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Beta-3 adrenergic receptor (Adrb3), partial

Recombinant Mouse Beta-3 adrenergic receptor (Adrb3), partial

  • 中文名稱：
    Recombinant Mouse Beta-3 adrenergic receptor(Adrb3),partial
  • 貨號：
    CSB-YP001393MO1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Beta-3 adrenergic receptor(Adrb3),partial
  • 貨號：
    CSB-EP001393MO1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Beta-3 adrenergic receptor(Adrb3),partial
  • 貨號：
    CSB-EP001393MO1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Beta-3 adrenergic receptor(Adrb3),partial
  • 貨號：
    CSB-BP001393MO1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Beta-3 adrenergic receptor(Adrb3),partial
  • 貨號：
    CSB-MP001393MO1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Adrb3; Adrb3r; B3bar; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
  • 基因功能參考文獻(xiàn)：
    1. In contrast, Adrb3 activation stimulates mature white adipocytes to convert into beige adipocytes. PMID: 29019320
    2. Specific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent beta3-adrenergic signaling. PMID: 28483278
    3. beta3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche. PMID: 28513874
    4. Findings are of potential physiologic importance as they uncover the antidiuretic effect of beta3-AR stimulation in the kidney. PMID: 27206969
    5. aerobic exercise training could improve cardiac systolic function and alleviate LV chamber dilation, cardiac fibrosis and hypertrophy in heart failure mice. The mechanism responsible for the protective effects of aerobic exercise is associated with the activation of the beta3-AR-nNOS-NO pathway. PMID: 28622359
    6. Data (including data from studies in knockout mice) suggest that Adrb3 is dispensable for browning of adipose tissue; here, no differences was observed in cold-induced thermogenic gene expression in brown, white, or beige adipose tissues due to absence of Adrb3; irrespective of duration of cold exposure or sex of mice, no effect of absence of Adrb3 was observed. PMID: 28223294
    7. injection of a b3-adrenergic receptor (b3-AR) agonist for continuous 5 days increased the number of Ki67-positive brown adipocytes even at Day 1 but not that of SV cells. In addition, the b3-AR antagonist, but not b1-AR antagonist, attenuated the cold exposure-induced increase in the number of Ki67-positive brown adipocytes PMID: 27846311
    8. ARbeta3 disruption does not affect brown adipose tissue thermogenesis but increases susceptibility to diet-induced obesity by dampening white adipose tissue lipolytic response to adrenergic stimulation. PMID: 27672060
    9. RIP140 has a unique role in the acute effect of beta-3 adrenergic receptor activation. PMID: 28322782
    10. Data show that fish oil intake increased oxygen consumption and rectal temperature, with concomitant upregulation of mitochondrial uncoupling protein 1 (UCP1) and beta3 adrenergic receptor (beta3AR). PMID: 26673120
    11. ADRB3 in perivascular adipose tissue contributes to vascular function in the progression of hypertension. PMID: 26910302
    12. Theseresultssuggestthat beta3-adrenoceptors are present in colonic Interstitial Cells of Cajal and may play a role in regulating gastrointestinal motility by the inhibition of pacemaker potentials. PMID: 25725113
    13. role of beta3-adrenoreceptor in myocardial infarction injury via eNOS and nNOS activation PMID: 24911015
    14. Nitric oxide is a downstream effector of beta3 adrenergic receptors which modulates melanoma cell proliferation. PMID: 24599317
    15. A single-dose administration of beta3AR agonist before reperfusion decreased infarct size and resulted in a consistent and long-term improvement in cardiac function in mouse model of myocardial ischemia reperfusion injury. PMID: 24951958
    16. Data suggest that Adrb3 is involved in regulation of pancreatic islet blood flow; hyperlipidemia (triglycerides and free fatty acids) is associated with vagus nerve-dependent increase in pancreatic/islet blood flow and up-regulation of insulin secretion. PMID: 25139049
    17. Beta3 adrenergic receptor activation lowers blood lipids and glucose which attenuates atherosclerotic plaque formation. PMID: 23892270
    18. activation of beta-adrenoceptor reduce the plaque area in the thoracic aorta and play an important anti-atherosclerotic role by regulating lipid metabolism disorders and the SR-B1 signal transduction pathway PMID: 23911886
    19. Beta3-adrenergic receptors modulate vascular endothelial growth factor release in response to hypoxia through the nitric oxide pathway in mouse retinal explants PMID: 23283573
    20. expression and function of beta(3)-adrenoceptors and beta(2)-adrenoceptors in mouse uterus PMID: 23219791
    21. beta(3)-adrenergic stimulation acts through up-regulation of E-selectin in adipose tissue endothelial cells to induce neutrophil infiltration PMID: 23235150
    22. Results suggest that the effects of zinc-alpha2-glycoprotein (ZAG) on body weight and insulin sensitivity in ob/ob mice are manifested through beta-adrenoreceptor (beta-AR) beta-3AR or possibly a beta2-AR. PMID: 22227600
    23. Brown adipocytes that are induced by beta3-adrenergic receptor activation in abdominal white adipose tissue arise from the proliferation and differentiation of cells expressing PDGFRalpha, CD34, and Sca-1. PMID: 22482730
    24. The function of M2 MR is substituted by beta3-AR and that these effects are mediated via adenylyl cyclase rather than NOS. PMID: 22222438
    25. Diminished beta3AR signaling may be the critical element to explain the direct effects of leptin on the myocardium and suggest that this work reveals a key feature in the role of leptin in obesity-related cardiac hypertrophy and heart failure. PMID: 21772246
    26. interaction of the beta(3a)-AR with caveolin inhibits coupling to Galpha(i/o) proteins and suggest that signaling is modulated by a raft-enriched complex containing the beta(3a)-AR, caveolin-1, Galpha(s), and adenylyl cyclase. PMID: 22535965
    27. NT-PGC-1alpha protein is sufficient to link AR beta 3 activation to transcriptional and physiological components of thermogenesis. PMID: 22282499
    28. High (stress) levels of epinephrine directly compromise the activity of neonatal mouse skin fibroblasts through the activation of beta1-, beta2- and beta3-adrenoceptors, but not through alpha1- and alpha2-adrenoceptors. PMID: 21366703
    29. b3-adrenoceptors are present in mouse astrocytes and activation of b2- and b3-adrenoceptors increases glucose uptake PMID: 21138422
    30. negative inotropy and heart hypertrophy occur in total adrenergic beta receptor deficiency PMID: 20406048
    31. Data show that both the mRNA and protein levels of beta2- and beta3-adrenergic receptors were up-regulated following cAMP/PKA-mediated adipogenesis of mouse bone marrow derived mesenchymal stem cells. PMID: 20363288
    32. genetic variants, including Ala/Ala of SCYA11 (eotaxin) Ala23Thr, Cys/Cys or Cys/Ser of PON2 (paraoxonase 2) Ser311Cys and Arg/Arg of ADRB3 (beta3-adrenergic receptor) Trp64Arg, were independently associated with incident cardiac end-point. PMID: 20536507
    33. Data show that caveolin-1 ablation affected neither the G-protein coupled LPA receptor signaling to Erk1/2, nor the receptor tyrosine kinases PDGF- or EGF-receptor signaling to Erk1/2. PMID: 20381543
    34. Both beta2- and beta3-AR are involved in MSC osteogenesis, with beta2-AR being dominant. PMID: 20138019
    35. Data suggest that glucocorticoids have opposing effects on beta(3)-adrenergic receptor gene expression: they rapidly and directly inhibit transcription but also induce a rapidly turned-over protein that stimulates gene transcription. PMID: 11997176
    36. betaAR signaling required for diet-induced thermogenesis and obesity resistance. PMID: 12161655
    37. role in obesity and cold sensitivity and response to fasting PMID: 12387862
    38. nuclear BAR-3 may have a role in eating behavior PMID: 12943691
    39. adrenergic stimulation, through beta3-adrenergic receptors/cAMP/protein kinase A, recruits a PI3K pathway stimulating conventional and novel PKCs, which mediate glucose uptake in brown adipocytes PMID: 14551227
    40. vimentin plays an essential role in the signal transduction pathway from beta3AR to the activation ERK and its contribution to lipolysis PMID: 17251187
    41. beta3-AR are upregulated during sepsis in the human myocardium and by cytokines in murine cardiomyocytes, where they mediate an increased negative inotropic response to beta3 agonists. PMID: 17999941
    42. Here we describe an atypical state of the beta(3)-adrenoceptor that exists endogenously in adipose tissue PMID: 18031735
    43. Report the effects of beta(3)-adrenoceptor agonist CL-316,243 on adiponectin, adiponectin receptors and tumor necrosis factor-alpha expressions in adipose tissues of obese diabetic KKAy mice. PMID: 18304529
    44. Norepinephrine signaling via beta(3) adrenergic receptors presumably in brown fat is the first neurotransmitter-receptor system identified that is required for normal recovery from torpor. PMID: 19107190
    45. while stimulation of the beta(3)AR leads to activation of CRE-dependent transcription, there are several pathways that converge at the level of CRE-response element activation, and for IL-6 this activation is mediated by p38 and PKC but not PKA pathways. PMID: 19477016
    46. Folic acid consumption has significant modulatory effects on beta-ARs protein expression and lipolysis. PMID: 19596833
    47. Functional beta(3)-adrenoceptors appear to be present in mouse urinary bladder. PMID: 19619525
    48. data suggest a cardioprotective role for the beta3-AR in modulating oxidative stress and adverse remodeling in the failing heart. PMID: 19766235

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamily
  • 組織特異性：
    White and brown adipose tissues, and digestive tract. Isoform B highest in brain.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产又大又粗又爽的毛片| 国产专区免费资源网站| 国产人妖乱国产精品人妖| 无码精品人妻一区二区三区免费看| 亚洲福利国产网曝| 国产日产亚洲系列最新美使用方法| 国产 制服丝袜 动漫在线| 日本护士毛茸茸| 香蕉av福利精品导航| 日韩精品无码免费一区二区三区| 久久天天躁狠狠躁夜夜2o2o| 日本精品人妻无码免费大全| 在线观看成人无码中文av天堂| 情人伊人久久综合亚洲| 夜夜爱夜夜做夜夜爽| 久久99国产综合精品女同| 国产成人一区二区三区app | 国产人妻鲁鲁一区二区| 全球成人中文在线| 18禁又污又黄又爽的网站不卡| 欧美又大又硬又粗bbbbb| 中文中幕a在线| 在线|国产精品女主播阳台| 精品少妇人妻av免费久久洗澡 | 国产av激情无码久久| 国产成+人+综合+亚洲 欧美| 久久亚洲国产精品五月天婷| 国产一三四2021不卡| av无码国产精品麻豆| 亚洲男人的天堂一区二区| 免费裸体美女网站| 久久99国产精品成人| 国产欧美日韩视频一区二区三区| 欧美乱大交xxxxx疯狂俱乐部| 久久久国产一区二区三区四区小说 | 欧美熟妇性xxx交潮喷| 色午夜一av男人的天堂| 麻豆精品人妻一区二区三区蜜桃 | 大地资源中文在线观看官网第二页| 欧美国产成人精品一区二区三区 | 日本wv一本一道久久香蕉|