在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse BTB/POZ domain-containing protein KCTD11 (Kctd11)

Recombinant Mouse BTB/POZ domain-containing protein KCTD11 (Kctd11)

  • 中文名稱：
    小鼠Kctd11重組蛋白
  • 貨號：
    CSB-YP811714MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Kctd11重組蛋白
  • 貨號：
    CSB-EP811714MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Kctd11重組蛋白
  • 貨號：
    CSB-EP811714MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Kctd11重組蛋白
  • 貨號：
    CSB-BP811714MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Kctd11重組蛋白
  • 貨號：
    CSB-MP811714MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Kctd11
  • Uniprot No.：
  • 別名：
    Kctd11; Ren; BTB/POZ domain-containing protein KCTD11; KCASH1 protein; Potassium channel tetramerization domain-containing protein 11; RING-type E3 ubiquitin transferase subunit KCTD11
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-232
  • 氨基酸序列
    MLGAMFRADT LMPANLNPQG DGHYFIDRDG KAFRHILNFL RLGRLDLPRG YGETALLKAE ADFYQIRPLL DALRELEASR GTPASTAALL HADVDVSPRQ VHFSARRGPH HYELSSVQVD TFRANLFCTD PECLAAMRNR FGVAIGDRAE GGPHFRLEWA SRPQELPEVE YQRLGLQPLW TGGPEDRREV ANTPTFLEEV LRVALEHGFR LDSVFPDPED LLNSRSLRFV RH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Acts as probable substrate-specific adapter for a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex towards HDAC1. Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcription factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. When knock-down, Hedgehog antagonism is impaired and proliferation of granule cells is sustained. Activates the caspase cascade.
  • 基因功能參考文獻：
    1. Results show negative regulation of HDAC1 by a Cul3-REN E3 ubiquitin ligase complex. PMID: 20081843
    2. REN is upregulated by neurogenic signals (retinoic acid, EGF, and NGF) in embryonal stem (ES) cells and neural progenitor cell lines in association with neurotypic differentiation. PMID: 12186855
    3. REN protein enhances caspase-3 activation and antagonizes the Shh pathway suggesting that this gene may represent a restraint of Shh signaling. PMID: 16148242
  • 組織特異性：
    Weakly expressed in lung. In the cerebellum, higher expression in non proliferating external granule cells layer than in highly proliferating ones.
  • 數據庫鏈接：


主站蜘蛛池模板： 波多野结衣av高清一区二区三区| 一本一道波多野结衣一区| 日日橹狠狠爱欧美视频| 亚洲精品无码成人av电影网| av永久天堂一区二区三区| 国产成人无码精品午夜福利a| 欧美506070老妇乱子伦| 99久久久国产精品消防器材| 亚洲乱码av中文一区二区| 久久久久久久极品内射| 黑人巨大无码中文字幕无码| 香蕉在线 亚洲 欧美 专区| 亚洲 中文字幕 日韩 无码| 国产高清视频一区三区| 天堂av无码大芭蕉伊人av不卡| 女人国产香蕉久久精品| 影视先锋av资源噜噜| 一本久道久久综合狠狠爱| 少妇精品偷拍高潮少妇小说| 极品少妇高潮到爽| 欧美午夜特黄aaaaaa片| 亚欧欧美人成视频在线| 久久国产人妻一区二区免费| 奇米影视7777久久精品| 免费国产a国产片高清| 久久久久 亚洲 无码 av 专区| 无码国产一区二区免费| 国产精品美女久久久免费| 在线亚洲日产一区二区| 亚洲综合久久无码色噜噜| 无码专区一va亚洲v专区在线| 国产尤物av尤物在线看| 99精品久久久久中文字幕| 欧美午夜精品一区二区蜜桃 | 亚洲欧洲日韩综合久久| 国产精品99精品无码视亚| 国产日韩欧美久久久精品图片| 亚洲午夜精品a片一区二区app| 国产免费无码一区二区三区| 亚洲va久久久噜噜噜久久天堂| 国产亚洲精品国产福利你懂的|