在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse BRISC complex subunit Abro1 (Fam175b)

Recombinant Mouse BRISC complex subunit Abro1 (Fam175b)

  • 中文名稱：
    Recombinant Mouse BRISC complex subunit Abro1(Fam175b)
  • 貨號：
    CSB-YP667536MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC complex subunit Abro1(Fam175b)
  • 貨號：
    CSB-EP667536MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC complex subunit Abro1(Fam175b)
  • 貨號：
    CSB-EP667536MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC complex subunit Abro1(Fam175b)
  • 貨號：
    CSB-BP667536MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC complex subunit Abro1(Fam175b)
  • 貨號：
    CSB-MP667536MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Abraxas2
  • Uniprot No.：
  • 別名：
    Abraxas2; Abro1; Fam175b; Kiaa0157BRISC complex subunit Abraxas 2; Abraxas brother protein 1; Protein FAM175B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-415
  • 氨基酸序列
    MAASISGYTF SAVCFHSANS NADHEGFLLG EVRQEETFSI SDSQISNTEF LQVIEIHNHQ PCSQLFSFYD YASKVNEESL DRILKDRRKK VIGWYRFRRN TQQQMSYREQ VIHKQLTRIL GVPDLVFLLF SFISTANNST HALEYVLFRP NRRYNQRISL AIPNLGNTSQ QEYKVSSVPN TSQSYAKVIK EHGTDFFDKD GVMKDIRAIY QVYNALQEKV QAVCADVEKS ERVVESCQAE VNKLRRQITQ KKNEKEQERR LQQALLSRQM PSESLEPAFS PRMSYSGFSA EGRSTLAETE PSDPPPPYSD FHPNNQESTL SHSRMERSVF MPRPQAVGSS SYASTSGGLK FTGSGADLLP SQSAAGDSGE ESDDSDYENL IDPAESPHSE YSHSKNSRPS THPDEDPRNT QTSQI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates. May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm. Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins. Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1. Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression. Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination. Required for normal induction of p53/TP53 in response to DNA damage. Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage.
  • 基因功能參考文獻：
    1. Abro1 deficiency results in increased chromosome instability, and Abro1-null mice are tumor-prone. PMID: 28860160
    2. Abraxas deficiency causes defective DNA repair, genetic instability, decreased survival and increased tumor incidence. PMID: 25066119
    3. Data shows that the expression of Abro1 protein substantially increased (at least three-fold) in the hearts of mice that underwent MI/R compared to sham operated controls. PMID: 21195082
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    FAM175 family, Abro1 subfamily
  • 組織特異性：
    Detected in heart (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲vs日韩vs欧美vs久久| 日韩一欧美内射在线观看| 18精品久久久无码午夜福利| 中文乱码字幕视频观看网站免费 | 免费国产成人午夜福利电影| 亚洲另类激情专区小说| 欧美亚洲综合在线一区| 午夜精品久久久内射近拍高清| 国产自偷在线拍精品热| 一区二区在线欧美日韩中文| 国产伦精品免编号公布| 九九视频在线观看视频6| 麻豆ā片免费观看在线看| 无码日韩精品一区二区三区免费 | 国产午夜片无码区在线观看| 亚洲电影在线观看| 无码少妇精品一区二区免费动态| 99视频精品全部免费免费观看| 97色精品视频在线观看| 精品久久久久久久久久久aⅴ| 亚洲人成无码网www电影麻豆 | 国产成人无码a区在线观看视频app| 亚洲成av人的天堂在线观看| 久久欧美国产伦子伦精品 | ww欧日韩视频高清在线| 天堂а√8在线最新版在线| 对白脏话肉麻粗话av| 久久精品av麻豆| 国产69精品久久久久乱码韩国 | 美国一区二区三区无码视频| 欧洲精品99毛片免费高清观看| 人妻洗澡被强公日日澡| 亚洲成av人片在线观看橙子| 精品国产品香蕉在线| 亚洲综合一区无码精品| 成人亚洲欧美久久久久| 粗大的内捧猛烈进出视频| 精品久久人人妻人人做精品| 麻豆视传媒精品av| 国产亚洲精品影视在线| 99久久无码一区人妻|