在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse BRISC and BRCA1-A complex member 1 (Babam1)

Recombinant Mouse BRISC and BRCA1-A complex member 1 (Babam1)

  • 中文名稱：
    Recombinant Mouse BRISC and BRCA1-A complex member 1(Babam1)
  • 貨號：
    CSB-YP661041MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC and BRCA1-A complex member 1(Babam1)
  • 貨號：
    CSB-EP661041MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC and BRCA1-A complex member 1(Babam1)
  • 貨號：
    CSB-EP661041MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC and BRCA1-A complex member 1(Babam1)
  • 貨號：
    CSB-BP661041MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse BRISC and BRCA1-A complex member 1(Babam1)
  • 貨號：
    CSB-MP661041MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Babam1
  • Uniprot No.：
  • 別名：
    Babam1; Merit40; Nba1BRISC and BRCA1-A complex member 1; Mediator of RAP80 interactions and targeting subunit of 40 kDa; New component of the BRCA1-A complex
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-333
  • 氨基酸序列
    MEVAEANSPT EEEEEEEEEG EETISEPRPH TRSNPEGAED RALGAQASVG SRSEGEGEAA TADGGAASVP GAGPKPWQVP ASASEVQIRT PRVNCPEKVI ICLDLSEEMS VPKLESFNGS RTNALNVSQK MVEMFVRTKH KIDKSHEFAL VVVNDDSAWL SGLTSDPREL CSCLYDLETA SCSTFNLEGL FSLIQQKTEL PVTENVQTIP PPYVVRTILV YSRPPCQPQF SLTEPMKKMF QCPYFFFDIV YIHNGTEEKE EDMSWKDMFA FMGSLDTKGA SYKYEVALAG PALELHNCMA KLLAHPLQRP CQTHASYSLL EEDEEAGEEE ATV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. In these 2 complexes, it is probably required to maintain the stability of BABAM2 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1. Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression. Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.
  • 基因功能參考文獻：
    1. Merit40 mutation exacerbated ICL-induced chromosome instability in the context of concomitant Brca2 deficiency but not in conjunction with Fancd2 mutation. PMID: 26338419
    2. MERIT40(-/-) hematopoietic stem cells are more resistant to cytoablative stress, and exhibit superior repopulating ability and self-renewal upon serial transplantation. PMID: 25636339
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    BABAM1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲国产精品成人午夜在线观看| 99久久超碰中文字幕伊人| 亚洲精品无码鲁网午夜| 熟女人妇 成熟妇女系列视频| 成人综合婷婷国产精品久久蜜臀 | 国产看真人毛片爱做a片| 一区二区无码免费视频网站| 国产免费人成网站x8x8| 国产综合色在线精品| 69精品人人人人| 国产av久久人人澡人人爱| 午夜福利不卡片在线机免费视频| 毛片无码免费无码播放| 色综合久久久久久久久久| 欧美毛多水多黑寡妇| 东京一本一道一二三区| 男女下面进入的视频免费午夜| 欧美一区二区三区激情| 亚洲成av人片在www| 亚洲精品少妇一区二区| 精品久久久久久| 日韩精品无码一区二区| 久久国产精品国产四虎90后| 精品久久久久久中文字幕大豆网| 人妻夜夜爽天天爽三区丁香花| 精品国产乱码久久久久app下载| 最近2019中文字幕在线| 天天夜碰日日摸日日澡性色av| 亚洲成a人片在线观看高清| av色国产色拍| 免费的av网站手机版| 欧美日韩精品一区二区三区不卡| 久久精品免费国产大片| 最新777第四色米奇影视| 人妻去按摩店被黑人按中出| 欧美 亚洲 国产 另类| 东北老女人高潮大喊舒服死了| 日韩内射美女人妻一区二区三区| 国模少妇一区二区三区| 99re8精品视频热线观看| 免费无码又爽又黄又刺激网站|