在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Autophagy-related protein 9A (Atg9a), partial

  • 中文名稱:
    Recombinant Mouse Autophagy-related protein 9A(Atg9a),partial
  • 貨號:
    CSB-YP737885MO1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Autophagy-related protein 9A(Atg9a),partial
  • 貨號:
    CSB-EP737885MO1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse Autophagy-related protein 9A(Atg9a),partial
  • 貨號:
    CSB-EP737885MO1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Autophagy-related protein 9A(Atg9a),partial
  • 貨號:
    CSB-BP737885MO1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse Autophagy-related protein 9A(Atg9a),partial
  • 貨號:
    CSB-MP737885MO1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Atg9a; Apg9l1; Autophagy-related protein 9A; APG9-like 1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB) in a process dependent on ARFIP2, but not ARFIP1. In addition to autophagy, also plays a role in necrotic cell death.
  • 基因功能參考文獻:
    1. Study find abnormalities of the bone surface in Atg9a knockout mice, suggesting an important role of Atg9a-dependent necrosis in bone surface formation. PMID: 27811852
    2. The AP-4 epsilon KO mouse is a suitable model for AP-4 deficiency syndrome, and defective mobilization of ATG9A from the TGN and impaired autophagic degradation of protein aggregates might contribute to neuroaxonal dystrophy in this disorder. PMID: 29698489
    3. the trafficking of Atg9A through the recycling endosomes is an essential step for autophagosome formation. PMID: 27587839
    4. Atg9a(-/-) fetal mice from pregnant dams heterozygous for both knockout alleles of Atg9a and p57(Kip2) are more susceptible to hypertensive stress than fetuses with intact autophagic machinery. PMID: 26370455
    5. Atg9a expression is required for neural stem cell differentiation. PMID: 24973144
    6. Both AMPK and ULK1 regulate localization of a critical component of the phagophore, ATG9. PMID: 22932492
    7. In the initial steps of Parkin-mediated mitophagy, the structures containing the ULK1 complex and Atg9A are independently recruited to depolarized mitochondria. PMID: 22275429
    8. Atg9Ap may be involved in autophagosome formation in the ER and axon terminals of neurons, the TGN, and lysosomes/late endosomes. PMID: 20124090

    顯示更多

    收起更多

  • 亞細胞定位:
    Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    ATG9 family
  • 數據庫鏈接:


主站蜘蛛池模板: 四虎永久在线精品免费观看| 欧美激情精品久久久久久| 在线观看国产成人av天堂| 伊人久久综合成人网| 超级碰97直线国产免费公开| 最激烈的床震娇喘视频出水| 最新国产在线拍揄自揄视频| 18精品久久久无码午夜福利| 欧美3p两根一起进高清免费视频| 欧美饥渴熟妇高潮喷水| 色综合无码av网站| 国产av国片精品jk制服丝袜 | 久久综合久久鬼色| 亚洲精品成人老司机影视| 久艾草在线精品视频在线观看| 欧美精品国产综合久久| 久爱www成人网免费视频| 99久久无码一区人妻| 中文成人无码精品久久久不卡| 成人性欧美丨区二区三区| 色噜噜狠狠色综合av| 亚洲色大成网站www国产| 精品一区二区三区在线观看视频 | 国产福利日本一区二区三区| 亚洲精品无码mv在线观看网站| 丰满少妇高潮惨叫久久久| 国产亚洲精品精品精品| 国产精品久久久久久| 日本免码va在线看免费| 中文字幕制服丝袜人妻动态图| 国产亚洲精品久久久久久牛牛| 狠狠人妻久久久久久综合| 日韩精品一区二区大桥未久| 精品国产成人高清在线观看| 无码国产伦一区二区三区视频| 久久香蕉国产线看观看怡红院妓院| 18勿入网站免费永久| 特黄熟妇丰满人妻无码| 色又黄又爽18禁免费网站现观看 | 影音先锋男人av鲁色资源网 | 少妇被粗大的猛烈进出动视频|