Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Asap2), partial

中文名稱：

Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(Asap2) ,partial
貨號：

CSB-YP742453MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(Asap2) ,partial
貨號：

CSB-EP742453MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(Asap2) ,partial
貨號：

CSB-EP742453MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(Asap2) ,partial
貨號：

CSB-BP742453MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2(Asap2) ,partial
貨號：

CSB-MP742453MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Asap2
Uniprot No.：

Q7SIG6
別名：

Asap2; Ddef2; Gm1523; Gm592Arf-GAP with SH3 domain; ANK repeat and PH domain-containing protein 2; Development and differentiation-enhancing factor 2; Paxillin-associated protein with ARF GAP activity 3; PAG3; Pyk2 C-terminus-associated protein; PAP
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.
基因功能參考文獻(xiàn)：
1. In conclusion, we have identified that ARL15 acts as an insulin-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1/PDPK1/AKT insulin pathway by interacting with its GAP ASAP2 and activating PDPK1. This research may provide new insights into GTPase-mediated insulin signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin sensitizati PMID: 28322786
亞細(xì)胞定位：

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups.
數(shù)據(jù)庫鏈接：

KEGG: mmu:211914

UniGene: Mm.358946