Recombinant Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(Apbb1ip)
貨號:
CSB-YP844466MO
規格:
來源:
Yeast
其他:
在線留言
中文名稱:
Recombinant Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(Apbb1ip)
貨號:
CSB-EP844466MO
規格:
來源:
E.coli
其他:
在線留言
中文名稱:
Recombinant Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(Apbb1ip)
貨號:
CSB-EP844466MO-B
規格:
來源:
E.coli
共軛:
Avi-tag Biotinylated
E. coli biotin ligase
(BirA) is highly specific in covalently attaching biotin to the 15 amino
acid AviTag peptide. This recombinant protein was biotinylated in vivo
by AviTag-BirA technology, which method is BriA catalyzes amide linkage
between the biotin and the specific lysine of the AviTag.
其他:
在線留言
中文名稱:
Recombinant Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(Apbb1ip)
貨號:
CSB-BP844466MO
規格:
來源:
Baculovirus
其他:
在線留言
中文名稱:
Recombinant Mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein(Apbb1ip)
Apbb1ip; Prel1Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; APBB1-interacting protein 1; Proline-rich EVH1 ligand 1; PREL-1; Proline-rich protein 48
The tag type will be
determined during production process. If you have specified tag
type, please tell us and we will develop the specified tag
preferentially.
產品提供形式:
Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶:
We recommend that this vial be briefly centrifuged prior
to opening to bring the contents to the bottom. Please reconstitute
protein in deionized sterile water to a concentration of 0.1-1.0
mg/mL.We recommend to add 5-50% of glycerol (final concentration) and
aliquot for long-term storage at -20℃/-80℃. Our default final
concentration of glycerol is 50%. Customers could use it as reference.
儲存條件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for
mutiple use. Avoid repeated freeze-thaw cycles.
保質期:
The shelf life is related to many factors, storage state,
buffer ingredients, storage temperature and the stability of the protein
itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The
shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期:
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our
proteins are default shipped with normal blue ice packs, if you
request to ship with dry ice, please communicate with us in advance
and extra fees will be charged.
注意事項:
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet :
Please contact us to get it.
產品評價
靶點詳情
功能:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
基因功能參考文獻:
These data identify the requirement of RIAM for formation of immunological synapses and in resulting T cell functions in autoimmunity. PMID: 28348273
we show that leukocyte integrin activation critically depends on RIAM both in vitro and in vivo PMID: 26337492
These in vivo results confirm a role for RIAM in the regulation of some, but not all, leukocyte integrins and suggest that RIAM-regulated integrin activation is required for trafficking of lymphocytes PMID: 26324702
crystal structure of an active, GTP-bound GTPase domain of Rap1 in complex with the Ras association (RA)-pleckstrin homology (PH) structural module of RIAM at 1.65 A, is reported. PMID: 24287201
generated RIAM-null mice and found that they are viable, fertile, and apparently healthy PMID: 25336629
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亞細胞定位:
Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns(5)P and PtdIns(3)P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases.
蛋白家族:
MRL family
組織特異性:
Ubiquitously expressed with high expression in the hematopoietic system.