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Recombinant Mouse Allergin-1 (Milr1), partial

In Stock
  • 中文名稱:
    小鼠Milr1重組蛋白
  • 貨號:
    CSB-EP662302MO
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP662302MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Milr1.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP662302MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Milr1.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Milr1
  • Uniprot No.:
  • 別名:
    Milr1; Gm885; Mca32; Allergin-1; Allergy inhibitory receptor 1; Mast cell antigen 32; MCA-32; Mast cell Ag-32; Mast cell immunoglobulin-like receptor 1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Extracellular Domain
  • 來源:
    E.coli
  • 分子量:
    20.1 kDa
  • 表達區域:
    34-150aa
  • 氨基酸序列
    ITLQNAAVDCTRVENNELPSPNLNSSMNVVRMGQNVSLSCSTKNTSVDITYSLFWGTKYLESKRRRGGAVDFHLRISNANESGPYKCKVNVSNLMKYSQDFNFTMAKDESCPSCRLS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
  • 基因功能參考文獻:
    1. The results suggest that Allergin-1 on skin MCs suppresses TLR2-induced dermatitis. PMID: 27932517
    2. It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
  • 組織特異性:
    Expressed in myeloid cells (dendritic cells, macrophages and neutrophils but not in T-cells, B-cells or natural killer cells) and mast cells (at protein level).
  • 數據庫鏈接:

    KEGG: mmu:380732

    UniGene: Mm.343952



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