在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Actin, alpha cardiac muscle 1 (Actc1)

  • 中文名稱:
    Recombinant Mouse Actin, alpha cardiac muscle 1(Actc1)
  • 貨號(hào):
    CSB-YP001221MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Actin, alpha cardiac muscle 1(Actc1)
  • 貨號(hào):
    CSB-EP001221MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse Actin, alpha cardiac muscle 1(Actc1)
  • 貨號(hào):
    CSB-EP001221MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Actin, alpha cardiac muscle 1(Actc1)
  • 貨號(hào):
    CSB-BP001221MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse Actin, alpha cardiac muscle 1(Actc1)
  • 貨號(hào):
    CSB-MP001221MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Actc1; ActcActin; alpha cardiac muscle 1; Alpha-cardiac actin) [Cleaved into: Actin; alpha cardiac muscle 1; intermediate form]
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    3-377
  • 氨基酸序列
    DDEETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP EEHPTLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VTHNVPIYEG YALPHAIMRL DLAGRDLTDY LMKILTERGY SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK SYELPDGQVI TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS LSTFQQMWIS KQEYDEAGPS IVHRKCF
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • 基因功能參考文獻(xiàn):
    1. This study provides novel insights into the complex genetic regulation of Actc1 expression in early adult skeletal muscles. PMID: 28847732
    2. Analogous to the findings in human skeletal muscle, Actc1 expression in mouse gastrocnemius muscle increased after testosterone deprivation in orchidectomized mice compared with sham controls PMID: 28756295
    3. ACTC E361G mutation uncouples the relationship between Ca(2+) sensitivity and troponin I phosphorylation, predisposing the heart to dilated cardiomyopathy under conditions of chronic stress. PMID: 26432839
    4. results demonstrate that in ACTC(Co)/KO myofibres, the presence of cardiac alpha-actin instead of skeletal muscle alpha-actin alters actin conformational changes upon activation; this later finely modulates the strain of individual actomyosin interactions and overall lowers myofibre force production PMID: 23784376
    5. Data indicate that the tri-helix bundle is important to the regulatory role of cMyBP-C, likely through actin-binding interactions. PMID: 23782699
    6. propose that the ACTC E99K mutation causes higher myofibrillar Ca(2+) sensitivity that is responsible for the sudden cardiac death, apical hypertrophy, and subsequent development of heart failure in humans and mice. PMID: 21622575
    7. Other actin isoforms cannot compensate for the lack of cardiac alpha-actin, and this seems to induce apoptosis in defective cardiac myocytes, which are not able to cope with the increased workload in the perinatal phase. PMID: 14605248
    8. These results demonstrate the importance of the Emb-MEF2D-histone transacetylase p300 complex in the transcriptional regulation of the cardiac actin gene and suggest a potential role in chromatin remodeling associated with muscle gene activation. PMID: 15024082
    9. there is a cardiac-specific enhancer located within -2.354/-1.36 kbp of Actc1 PMID: 15491989

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Actin family
  • 數(shù)據(jù)庫鏈接:

    KEGG: mmu:11464

    STRING: 10090.ENSMUSP00000087736

    UniGene: Mm.686



主站蜘蛛池模板: 国产在线精品一区在线观看| 好日子在线观看视频大全免费动漫| 国产欧美va天堂在线电影| 97精品免费公开在线视频| 欧美在线观看免费专区| 亚洲人成网站在线观看69影院| 69久久精品无码一区二区| 亚洲美女精品免费视频| 亚洲色大成网站www永久在线观看| 十八禁av无码免费网站| 熟女性饥渴一区二区三区| 久久精品人妻少妇一区二区三区| 亚洲性人人天天夜夜摸| 亚洲国产成人久久一区久久| 美国人性欧美xxxx| 成人精品视频99在线观看免费| 韩国精品福利一区二区三区| 草草久久97超级碰碰碰| 色琪琪丁香婷婷综合久久| 久久精品无码专区免费| 中国女人内谢69xxxx| 国产精品无码电影在线观看| 亚洲 欧美 另类 综合 日韩| 99精品免视看| 久久婷婷五月综合色中文字幕| 丰满大爆乳波霸奶| 亚洲乱码中文论理电影| 好硬好湿好爽再深一点动态图视频 | 正在播放的国产a一片| 三级理论中文字幕在线播放| 2020久热爱精品视频在线观看 | 色翁荡熄又大又硬又粗又视频图片| 中国性少妇内射xxxx狠干| 天天综合网亚在线| 欧美最猛黑人xxxxx猛交| 99re6在线视频精品免费下载 | 日本丰满护士videossexhd| 成人精品视频99在线观看免费| 亚洲aⅴ无码国精品中文字慕| 久久精品日日躁夜夜躁| 久久精品国产精品亚洲毛片 |