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  4. Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15 (Adamts15)

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15 (Adamts15)

  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15(Adamts15)
  • 貨號：
    CSB-YP001303MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15(Adamts15)
  • 貨號：
    CSB-EP001303MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15(Adamts15)
  • 貨號：
    CSB-EP001303MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15(Adamts15)
  • 貨號：
    CSB-BP001303MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 15(Adamts15)
  • 貨號：
    CSB-MP001303MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Adamts15
  • Uniprot No.：
  • 別名：
    Adamts15; A disintegrin and metalloproteinase with thrombospondin motifs 15; ADAM-TS 15; ADAM-TS15; ADAMTS-15; EC 3.4.24.-
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    213-950
  • 氨基酸序列
    FVSIPRYV ETLVVADESM VKFHGADLEH YLLTLLATAA RLYRHPSILN PINIVVVKVL LLGDRDTGPK VTGNAALTLR NFCAWQKKLN KVSDKHPEYW DTAILFTRQD LCGATTCDTL GMADVGTMCD PKRSCSVIED DGLPSAFTTA HELGHVFNMP HDNVKVCEEV FGKLRANHMM SPTLIQIDRA NPWSACSAAI ITDFLDSGHG DCLLDQPSKP ITLPEDLPGT SYSLSQQCEL AFGVGSKPCP YMQYCTKLWC TGKAKGQMVC QTRHFPWADG TSCGEGKFCL KGACVERHNP NKYRVDGSWA KWEPYGSCSR TCGGGVQLAR RQCSNPTPAN GGKYCEGVRV KYRSCNLEPC PSSASGKSFR EEQCEAFNGY NHSTNRLTLA VAWVPKYSGV SPRDKCKLIC RANGTGYFYV LAPKVVDGTL CTPDSTSVCV QGKCIKAGCD GNLGSKKKFD KCGVCGGDNK SCKRVTGLFT KPMHGYNFVV AIPAGASSID IRQRGYKGLI GDDNYLALKN SQGKYLLNGH FVVSAVERDL VVKGSVLRYS GTGTAVESLQ ASRPILEPLT VEVLSVGKMT PPRVRYSFYL PKEPREDKST RPKDPRGSPV LRNSVLSLSN QVEQPDNRPP ARWVAGSWGP CSVSCGSGLQ KRAVDCRDSP GQQGASACDV DHRPLEKRAC GEPCPTWELG NWSPCSKSCG RGFKRRPLKC VGHGGRLLAR DQCDLRRKPQ ELDFCVLRPC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1401-|-1402-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.
  • 基因功能參考文獻：
    1. spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts15 in mice. PMID: 25510509
    2. Results show that ADAMTS15 and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development PMID: 25349050
    3. these data suggest a role for ADAMTS15 in a wide range of biological processes that are potentially mediated through the processing of versican. PMID: 24220035
  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix. Cell surface.
  • 組織特異性：
    At 10.5 dpc, strongly and specifically expressed in the developing heart tubes. By 13.5 dpc, widely expressed including in the perichondrium in the developing autopod, brain, ear, whisker follicles, vertebral column and epidermis. Also localizes to the my
  • 數據庫鏈接：

    KEGG: mmu:235130

    UniGene: Mm.65867



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