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  4. Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), partial

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12 (Adamts12), partial

  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12(Adamts12) ,partial
  • 貨號：
    CSB-YP802274MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12(Adamts12) ,partial
  • 貨號：
    CSB-EP802274MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12(Adamts12) ,partial
  • 貨號：
    CSB-EP802274MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12(Adamts12) ,partial
  • 貨號：
    CSB-BP802274MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 12(Adamts12) ,partial
  • 貨號：
    CSB-MP802274MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Adamts12
  • Uniprot No.：
  • 別名：
    Adamts12A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS 12; ADAM-TS12; ADAMTS-12; EC 3.4.24.-
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Metalloprotease that plays a role in the degradation of COMP. Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties.
  • 基因功能參考文獻：
    1. ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review] PMID: 24876675
    2. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis. PMID: 23019333
    3. ADAMTS-12 plays protective roles acting against the development of asthma phenotype upon experimental allergen exposure, interfering with immunological processes leading to inflammation and airway hyperresponsiveness. PMID: 22962682
    4. Results define a break point in mouse chromosome 15qA1 to a 27-kb region containing ADAMTS12, and show that the break is likely between exons 2 and 3 of ADAMTS12. PMID: 20412686
    5. Absence of Adamts-12 is associated with the increase in angiogenic response and tumor invasion into host tissue. PMID: 20208563

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  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 數(shù)據(jù)庫鏈接：


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