在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial (Alas2)

Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial (Alas2)

  • 中文名稱：
    Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial(Alas2)
  • 貨號(hào)：
    CSB-YP001560MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial(Alas2)
  • 貨號(hào)：
    CSB-EP001560MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial(Alas2)
  • 貨號(hào)：
    CSB-BP001560MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse 5-aminolevulinate synthase, erythroid-specific, mitochondrial(Alas2)
  • 貨號(hào)：
    CSB-MP001560MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Alas2
  • Uniprot No.：
  • 別名：
    Alas2; 5-aminolevulinate synthase; erythroid-specific; mitochondrial; ALAS-E; EC 2.3.1.37; 5-aminolevulinic acid synthase 2; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    50-587
  • 氨基酸序列
    Q IHLKATKAGG DSPSWAKSHC PFMLSELQDR KSKIVQRAAP EVQEDVKTFK TDLLSTMDST TRSHSFPSFQ EPEQTEGAVP HLIQNNMTGS QAFGYDQFFR DKIMEKKQDH TYRVFKTVNR WANAYPFAQH FSEASMASKD VSVWCSNDYL GISRHPRVLQ AIEETLKNHG AGAGGTRNIS GTSKFHVELE QELAELHQKD SALLFSSCFV ANDSTLFTLA KLLPGCEIYS DAGNHASMIQ GIRNSGAAKF VFRHNDPGHL KKLLEKSDPK TPKIVAFETV HSMDGAICPL EELCDVAHQY GALTFVDEVH AVGLYGARGA GIGERDGIMH KLDIISGTLG KAFGCVGGYI ASTRDLVDMV RSYAAGFIFT TSLPPMVLSG ALESVRLLKG EEGQALRRAH QRNVKHMRQL LMDRGFPVIP CPSHIIPIRV GNAALNSKIC DLLLSKHSIY VQAINYPTVP RGEELLRLAP SPHHSPQMME NFVEKLLLAW TEVGLPLQDV SVAACNFCHR PVHFELMSEW ERSYFGNMGP QYVTTYA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. we used bioinformatics and computational biology tools to evaluate the role(s) of the C-terminal tail dynamics in the structure and conformational dynamics of the murine ALAS2 homodimer active site loop. PMID: 29958424
    2. Data indicate that the 5-aminolevulinate synthase (mALAS2) active site loop harboring the simultaneous seven amino acid mutations was less flexible than the wild type loop. PMID: 27928941
    3. We propose that the N-terminal truncation offers a cell-specific ALAS2 regulatory mechanism without hindering heme synthesis PMID: 26854603
    4. N150F ALAS variant catalyzes the forward reaction at a mere 1.2-fold faster rate than that of the reverse reaction. PMID: 26511319
    5. Light treatments revealed that ALAS2 expression results in an increase in cell death in comparison to aminolevulinic acid (ALA) treatment producing a similar amount of protoprophyrin IX. PMID: 24718052
    6. The rate of ALA release is also controlled by a hysteretic kinetic mechanism (observed as a lag in the ALA external aldimine formation progress curve), consistent with conformational changes governing the dissociation of ALA from ALAS. PMID: 24920668
    7. impaired mitochondrial [Fe-S] cluster biogenesis in Mfrn1(gt/gt) cells results in elevated IRP1 RNA-binding that attenuates ALAS2 mRNA translation and protoporphyrin accumulation PMID: 24509859
    8. Data suggest the reaction of glycine with ALAS follows a three-step kinetic process, and the substrate 5-aminolevulinate induces a conformational change in ALAS which may modulate product release. PMID: 12191993
    9. Aberrant iron accumulation and peroxidized state of (ALAS2)-deficient definitive erythroblasts PMID: 12393610
    10. mechanism of up-regulation in erythroleukemia cells exposed to hypoxia PMID: 12393745
    11. These findings thus suggest that heme may regulate a wide variety of hitherto unrecognized genes, and further analysis of these genes may clarify their role in erythroid cell differentiation. PMID: 16356476
    12. Gene expression and enzymatic assays indicate that erythroid 5-aminolevulinic acid synthase (Alas2) is decreased in hem6 animals, suggesting a mechanism that could account for the anemia. PMID: 18780836

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-II pyridoxal-phosphate-dependent aminotransferase family
  • 組織特異性：
    Erythroid specific.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产乱人伦精品一区二区在线观看 | 夜夜春夜夜爽| 999zyz玖玖资源站永久| 成人试看30分钟免费视频| 亚洲精品成人久久电影网| 在线a久青草视频在线观看| 亚洲成av人无码综合在线观看| 日本老妇人乱xxy| 日本高清色www网站色噜噜噜| 国产午夜理论不卡在线观看| 欧美巨大巨粗黑人性aaaaaa| 欧美性猛交xxxx免费看| 日韩人妻无码一区二区三区综合| 18禁黄久久久aaa片| 亚洲天天做日日做天天谢日日欢| 性夜夜春夜夜爽aa片a| 2020精品国产午夜福利在线观看| 无码丰满熟妇bbbbxxx| 成人精品视频99在线观看免费| 国产成人综合欧美精品久久| 中文字幕无码精品三级在线电影 | 亚洲乱色伦图片区小说| 亚洲另类激情专区小说| 无套内内射视频网站| 日韩av无码久久一区二区| 亚洲一线产区二线产区分布| 亚洲中文字幕无码久久| 男女高潮又爽又黄又无遮挡| 国产99在线 | 免费| 日本一道高清一区二区三区| 成人性做爰aaa片免费看不忠| 久久96国产精品久久久| av激情亚洲男人的天堂| 欧美性潮喷xxxxx免费视频看| 欧美熟妇xxxxx欧美老妇不卡| 华人在线亚洲欧美精品| 久久精品人人做人人综合| 国产卡一卡二卡三无线乱码新区 | 中文字幕欧美亚州视频免费| 男女性爽大片视频| 国产激情久久久久影院小草|