在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse 5' exonuclease Apollo (Dclre1b)

Recombinant Mouse 5' exonuclease Apollo (Dclre1b)

  • 中文名稱：
    Recombinant Mouse 5' exonuclease Apollo(Dclre1b)
  • 貨號：
    CSB-YP804925MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse 5' exonuclease Apollo(Dclre1b)
  • 貨號：
    CSB-EP804925MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse 5' exonuclease Apollo(Dclre1b)
  • 貨號：
    CSB-EP804925MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse 5' exonuclease Apollo(Dclre1b)
  • 貨號：
    CSB-BP804925MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse 5' exonuclease Apollo(Dclre1b)
  • 貨號：
    CSB-MP804925MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dclre1b
  • Uniprot No.：
  • 別名：
    Dclre1b; Snm1b; 5' exonuclease Apollo; EC 3.1.-.-; DNA cross-link repair 1B protein; SNM1 homolog B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-541
  • 氨基酸序列
    MNGVVIPQTP IAVDFWSLRR AGSARLFFLT HMHCDHTVGL SSTWARPLYC SPITACLLHR RLQVSKHWIR ALEVGESHVL PLDEIGQETM TVTLIDANHC PGSVMFLFEG YFGTILYTGD FRYTPSMLKE PALILGKQIH TLYLDNTNCN PALVLPSRQE ATQQIVQLIR QFPQHNIKIG LYSLGKESLL EQLALEFRTW VVLSPQRLEL VQLLGLADVF TVEEEAGRIH AVDHTEICHS AMLQWNQSHP TIAIFPTSRK VRSPHPSIYT VPYSDHSSYS ELRAFVAALR PCQVVPIVHQ KPCGEFFQDS LSPRLAMPLI PHSVQQYMSS SSRKTNVLWQ LERRLKRPRT QGVVFESPEE KANQVKVDRD SKKHKKENLS PWAGHLERLC PHPLQARKQL FPDFCRKERD EPVLFCDSNK MATVLTAPLE FSVQLQPIDE FLFPETREKI GLESPLLSRG DSGSPARGNQ SDCVGCGSPP AHISRAVPLT PESRGLALKY LLTPVHFLQA GFSSRNFDKQ VEKHQRVQRS SPAVLSPVDV G
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint. Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin. Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem).
  • 基因功能參考文獻：
    1. The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development PMID: 20854421
    2. TRF2-bound Apollo functions at replicating telomeres, promoting the maintenance of the telomeric overhang, repressing S phase-specific ATM signaling, and protecting leading-end telomeres from fusion. PMID: 20619712
    3. Apollo null mouse embryo fibroblasts exhibit an increased incidence of G2 chromatid-type fusions involving telomeres created by leading-strand DNA synthesis, reflective of a failure to protect these telomeres after DNA replication. PMID: 20551906
  • 亞細胞定位：
    Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.
  • 蛋白家族：
    DNA repair metallo-beta-lactamase (DRMBL) family
  • 數據庫鏈接：


主站蜘蛛池模板： 精品一区二区ww| 亚洲熟妇无码av| 欧美亚洲色综久久精品国产| 国产精品人妻一码二码尿失禁 | 国产饥渴孕妇在线播放| 精品免费国偷自产在线视频| 又白又嫩毛又多15p| 扒开双腿吃奶呻吟做受视频 | 欧美日韩亚洲tv不卡久久| 无码免费中文字幕视频| 野外做受三级视频| 中文字幕乱码中文乱码777| 欧美精品欧美人与动人物牲交| 国产午夜成人无码免费| 亚洲日韩中文字幕在线播放| 国产乡下妇女做爰| 亚洲乱码日产精品bd在线看| 日本成本人三级在线观看| 成人av无码国产在线观看| 色婷婷一区二区三区四区成人网| 亚洲精品久久久久久动漫器材一区| 免费国产黄网在线观看| 污污污污污污污网站污| 新国产三级视频在线播放| 天堂а√中文最新版地址在线| 国产毛片不卡野外视频| 欧美黑人xxxx性高清版| 国内老熟妇对白xxxxhd| 亚洲一线二线三线写真| 亚洲欧美日本中文字不卡 | 人妻巨大乳一二三区| 成全世界免费高清观看| 亚洲色无码专区一区| 久久精品国产久精久精| 毛片无码一区二区三区a片视频| 亚洲人成网站在线播放影院在线 | 99国产精品久久久久久久成人| 色猫咪免费人成网站在线观看| 狠狠噜天天噜日日噜视频麻豆| 亚洲国产精品无码一线岛国| 男女性潮高清免费网站|