在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase (Cyp7b1)

  • 中文名稱:
    Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase(Cyp7b1)
  • 貨號:
    CSB-YP733726MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase(Cyp7b1)
  • 貨號:
    CSB-EP733726MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase(Cyp7b1)
  • 貨號:
    CSB-EP733726MO-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase(Cyp7b1)
  • 貨號:
    CSB-BP733726MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse 25-hydroxycholesterol 7-alpha-hydroxylase(Cyp7b1)
  • 貨號:
    CSB-MP733726MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Cyp7b1
  • Uniprot No.:
  • 別名:
    Cyp7b1Cytochrome P450 7B1; 24-hydroxycholesterol 7-alpha-hydroxylase; EC 1.14.14.26; 25/26-hydroxycholesterol 7-alpha-hydroxylase; EC 1.14.14.29; 3-hydroxysteroid 7-alpha hydroxylase; Hippocampal transcript 1 protein; HCT-1; Oxysterol 7-alpha-hydroxylase
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-507
  • 氨基酸序列
    MQGATTLDAA SPGPLALLGL LFAATLLLSA LFLLTRRTRR PREPPLIKGW LPYLGMALKF FKDPLTFLKT LQRQHGDTFT VFLVGKYITF VLNPFQYQYV TKNPKQLSFQ KFSSRLSAKA FSVKKLLTDD DLNEDVHRAY LLLQGKPLDA LLETMIQEVK ELFESQLLKI TDWNTERIFA FCGSLVFEIT FATLYGKILA GNKKQIISEL RDDFFKFDDM FPYLVSDIPI QLLRNEESMQ KKIIKCLTSE KVAQMQGQSK IVQERQDLLK RYYRHDDPEI GAHHLGFLWA SLANTIPAMF WAMYYILRHP EAMEALRDEI DSFLQSTGQK KGPGISVHFT REQLDSLVCL ESTILEVLRL CSYSSIIREV QEDMNLSLES KSFSLRKGDF VALFPPLIHN DPEIFDAPKE FRFDRFIEDG KKKSTFFKGG KKLKTYVMPF GLGTSKCPGR YFAVNEMKLL LIMLLTYFDL EIIDRKPIGL NHSRMFLGIQ HPDSAVSFRY KAKSWRS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    A cytochrome P450 monooxygenase involved in the metabolism of endogenous oxysterols and steroid hormones, including neurosteroids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of steroids with a preference for 7-alpha position. Usually metabolizes steroids carrying a hydroxy group at position 3, functioning as a 3-hydroxy steroid 7-alpha hydroxylase. Hydroxylates oxysterols, including 25-hydroxycholesterol and (25R)-cholest-5-ene-3beta,26-diol toward 7-alpha hydroxy derivatives, which may be transported to the liver and converted to bile acids. Via its product 7-alpha,25-dihydroxycholesterol, a ligand for the chemotactic G protein-coupled receptor GPR183/EBI2, regulates B cell migration in germinal centers of lymphoid organs, thus guiding efficient maturation of plasma B cells and overall antigen-specific humoral immune response. 7-alpha hydroxylates neurosteroids, including 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone) and pregnenolone, both involved in hippocampus-associated memory and learning. Metabolizes androstanoids toward 6- or 7-alpha hydroxy derivatives.
  • 基因功能參考文獻(xiàn):
    1. Increasing 27-hydroxycholesterol concentrations by genetic means leads to decrease bone mineral density. PMID: 20501668
    2. Because CYP7B1 represents the major pathway for inactivating 3betaAdiol in the prostate, we suggest that ERbeta, 3betaAdiol, and CYP7B1 are the components of a pathway that regulates growth of the rodent ventral prostate. PMID: 12370428
    3. Identification of Cyp7b1 as a novel RORalpha (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3). PMID: 18055760
    4. CYP7B1-mediated catalysis may play a role for control of the cellular levels of androgens, not only of estrogens. PMID: 19732851
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cytochrome P450 family
  • 組織特異性:
    Highly expressed in brain structures including the corpus callosum, the anterior commissure and fornix. The hippocampal expression is particularly prominent in the dentate gyrus. Expressed in liver and kidney. The hepatic expression is sexually dimorphic,
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 少妇的渴望hd高清在线播放| 99久久精品国产成人综合| 波多老师无码av中字专区| 亚洲午夜未满十八勿入| 亚洲人成无码网站| 女人的精水喷出来视频 | 国产日产欧产精品精品免费| 国产精品日本亚洲777| 制服 丝袜 人妻 专区一本| 国产精品熟妇视频国产偷人| 色翁荡息又大又硬又粗又爽| 蜜臀久久99精品久久久久久做爰| 日韩av无码中文无码电影| 性xxxx欧美老妇506070| 亚洲国产av无码精品| 成人片黄网站a毛片免费| 亚洲中文久久精品无码照片| 国产明星裸体xxxx视频| 初尝黑人嗷嗷叫中文字幕| 曰曰摸夜夜添夜夜添高潮出水| 亚洲一本大道av久在线播放| 麻豆日产精品卡2卡3卡4卡5卡| 一本久道综合色婷婷五月| 国产三级av在线播放| 欧美国产日韩a在线视频| 亚洲第一无码专区天堂| 女人被狂躁高潮啊的视频在线看| 永久黄网站色视频免费直播| 高清一区二区三区日本久| 真人做受试看120分钟小视频| 国产午夜福利内射青草| 大黑人交xxxx18视频| 亚洲日韩乱码久久久久久| 日本一区二区三区免费更新不卡| 亚洲天堂在线观看完整版| 熟女性饥渴一区二区三区| 日本亲近相奷中文字幕| 国产日产欧产精品精品免费| 伊人久久亚洲综合影院首页| 久久大香香蕉国产| 亚洲精品久久久久高潮|