在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (Plcd1)

Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (Plcd1)

In Stock
  • 中文名稱：
    小鼠Plcd1重組蛋白
  • 貨號：
    CSB-BP854509MO
  • 規(guī)格：
    ￥3168
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 85% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length
  • 來源：
    Baculovirus
  • 分子量：
    91.5 kDa
  • 表達區(qū)域：
    1-756aa
  • 氨基酸序列
    MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADVQHWVQGLRKIIDRSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKEVKDFLKELNVQVDDSYARKIFRECDHSQTDSLEDEEIETFYRMLTQRAEIDRAFAEAAGSAETLSVEKLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMNQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMAHHLRAILGPMLLDQPLDGVTTSLPSPEQLKEKILLKGKKLGGLLPAGGENGPEATDVSDEDEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMVIYCKSVHFGGFSSPSTSGQAFYEMASFSESRALRLLQESGNSFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPDTTFNSRALTQGPWWAPKKLRVWIISGQQLPKVNKNKNSIVDPKVIVEIHGVGQDVASRQTAVITNNGFNPRWDTEFEFVVAVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDLHPSATLFVKISIQD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development. Binds phosphatidylinositol 4,5-bisphosphate.
  • 基因功能參考文獻：
    1. Data show that phospholipase C delta1 (PLCD1) transfection can induce the apoptosis of CAPAN-1 and BXPC-3 pancreatic cancer cells, arrest the cell cycle in G0 /G1 phase. PMID: 27371838
    2. the Ca(2+) dependence of the interaction between PRIP-C2 and Syt1-C2A was attributed to Ca(2+) binding with Syt1-C2A, but not PRIP-C2, using a series of mutants prepared from both C2 domains. PMID: 25242442
    3. Results indicate that PLCdelta1 and PLCdelta3 are required for cardiomyocyte survival and normal cardiac function. PMID: 24810051
    4. Expression of PLCdelta1 is increased in ALS mouse spinal cord and in neurons from ALS mice. Genetic ablation of this protein in ALS mice significantly increases survival PMID: 23969236
    5. Identification, characterization and regulatory properties of a novel PLCD1 isoform in mouse. PMID: 23892088
    6. Plcd1 and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface. PMID: 22723964
    7. Loss of phospholipase Cdelta1 from keratinocytes causes features of interleukin-17-associated inflammatory skin diseases. PMID: 22805570
    8. PLCdelta1 has essential roles in thermogenesis and adipogenesis and thereby contributes to the development of obesity. PMID: 21617180
    9. Results suggest that phospholipase C delta(1) is required for skin stem cell lineage commitment. PMID: 12805213
    10. the PLC-delta1 promoter is under the control of NF-kappaB, which mediates the expression of PLC-delta due to Abeta42 PMID: 14550290
    11. PLCdelta(1) and PLCdelta(4) are probably differentially regulated in distinct cellular compartments by PI(4,5)P(2) PMID: 15037625
    12. Nuclear translocation of phospholipase C-delta1 is linked to the cell cycle and nuclear phosphatidylinositol 4,5-bisphosphate PMID: 15809301
    13. Data indicate that receptor-triggered phospholipase C activity is enhanced by positive feedback from Ca2+ entering the cytoplasm from intracellular stores and via store-operated channels in the plasma membrane. PMID: 16159958
    14. PLCdelta1 and PLCdelta3 are essential in trophoblasts for placental development. PMID: 16314520
    15. Taken together, these results indicate that lack of PLC-delta1 induces skin inflammation and that the epidermal hyperplasia in PLC-delta1 KO mice is caused by skin inflammation. PMID: 17397799
    16. These results indicate that PLC-delta1 is an essential molecule downstream of Foxn1 in normal hair formation, and strongly suggest that hairlessness in nude mice is caused by insufficient expression of PLC-delta1. PMID: 17938256
    17. PLCd1 is essential for normal hair formation, and PLCd1 KO mice displayed symptoms of skin inflammation. PLCdelta 1 KO mice possess skin phenotype similar to nude mice. PMID: 18177742

    顯示更多

    收起更多

  • 組織特異性：
    Highly expressed in brain, heart, lung, epididymis and testis. Detected at lower levels in kidney and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 中文字幕人乱码中文字幕| 九九久久精品国产免费看小说 | 久久久久国产精品人妻aⅴ院| 天天躁日日躁狠狠躁性色av| 午夜色大片在线观看| 男人添女人下部高潮全视频| 性色av一区二区三区无码| 国产成人a人亚洲精品无码 | 日韩日韩日韩日韩日韩| 小说区亚洲综合第1页| 久久精品国自产拍| 99久久亚洲精品无码毛片| 久久久亚洲欧洲日产国码农村| 亚洲成色综合网站在线| 香蕉久久国产超碰青草| 波多野结衣av在线观看| 夜夜爽妓女8888视频免费观看| 亚洲第一极品精品无码 | 亚洲午夜久久久久妓女影院| 欧美成人午夜性视频| 国产亚洲精品字幕在线观看| 亚洲人成电影在线播放| 午夜无码福利伦利理免| 国产亚洲精品资源在线26u| 中文字幕乱码人妻综合二区三区| 久章草国语自产拍在线观看| 亚洲手机在线人成网站| 国产熟妇乱xxxxx大屁股网| 三上悠亚人妻中文字幕在线| 伊人久久大香线蕉av综合| 午夜三级a三级三点在线观看| 三级4级全黄60分钟| 精品国内自产拍在线播放观看| 少妇无码av无码专区线y| 天天躁夜夜躁av天天爽| 狠狠色综合网站久久久久久久| 国产精品亚洲玖玖玖在线观看| 国产无遮挡又黄又爽免费视频| 精品人妻无码一区二区三区换脸| 丰满的少妇xxxxx人| 夜夜躁狠狠躁日日躁视频|