在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (Plcb3), partial

Recombinant Mouse 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (Plcb3), partial

  • 中文名稱：
    小鼠Plcb3重組蛋白
  • 貨號：
    CSB-YP018128MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Plcb3重組蛋白
  • 貨號：
    CSB-EP018128MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Plcb3重組蛋白
  • 貨號：
    CSB-EP018128MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Plcb3重組蛋白
  • 貨號：
    CSB-BP018128MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Plcb3重組蛋白
  • 貨號：
    CSB-MP018128MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  • 基因功能參考文獻：
    1. Data, including data from studies using transgenic/knockout mice, suggest that Ppp1ca and Gnb1 interact in quiescent platelets; then, Ppp1ca and Plcb3 interact during platelet aggregation; thus, Gnb1 enlists Ppp1ca to modulate G protein-coupled receptor signaling. (Ppp1ca = protein phosphatase 1, catalytic subunit alpha; Gnb1 = guanine nucleotide-binding protein, subunit beta-1; Plcb3 = phospholipase C, subunit beta-3) PMID: 28615442
    2. Plcb3-deficient mice spontaneously develop atopic dermatitis-like skin lesions. PMID: 24412367
    3. Data suggest that PLCbeta3 acts as a negative regulator of VEGF- (vascular endothelial growth factor A-) mediated vascular hyperpermeability through intracellular calcium signaling. PMID: 22674805
    4. defined a PLC-beta3- and SHP-1-mediated signaling pathway for FcvarepsilonRI-mediated cytokine production PMID: 21683628
    5. Cellular G(i)-G(q) synergism derives from direct supra-additive stimulation of phospholipase C-beta3 by G protein subunits Gbetagamma and Galpha(q). PMID: 20579885
    6. Expression of Plcb3 was studied in a cell line during myoblast differentiation. PMID: 15174099
    7. results suggest that activation of PLC-b3 by pertussis toxin-sensitive G proteins is responsible for transient [Ca2+]i increase in response to thrombin PMID: 15995354
    8. GPCR agonists ET-1, LPA, and thrombin activate PLCepsilon and PLCbeta3 in fibroblasts. Activation of these PLC isoforms displays agonist-specific temporal profiles; PLCbeta3 is predominantly involved in acute and PLCepsilon in sustained PI hydrolysis PMID: 16314422
    9. The pattern of phospholipase Cbeta3 expression is unique, revealing stripes in three of the four transverse zones and a uniform distribution in the fourth. and PLCbeta3 is restricted to the zebrin II-immunopositive Purkinje cell subset. PMID: 16566000
    10. These results demonstrate that PLCbeta3 is required to mediate "itch" sensation in response to histamine acting on the histamine H1 receptor in C-fiber nociceptive neurons. PMID: 17114052
    11. PLCbeta3 plays a major role in mediating mGluR1-dependent synaptic transmission, plasticity, and integration in PLCbeta3-dominant Purkinje cells PMID: 17298601
    12. a novel role for PLC activity in promoting macrophage survival in atherosclerotic plaques and identify PLC beta3 as a potential target for treatment of atherosclerosis. PMID: 18079968
    13. PLCbeta3 may provide a selective target for inhibiting Ca(2+) responses to mediators of inflammation, including C5a, UDP, PAF, and LPA PMID: 18411281
    14. Deficiencies in PLC-beta3 are associated with the development of myeloproliferative disease, lymphoma, and other tumors. PMID: 19647226

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Membrane. Nucleus.
  • 組織特異性：
    Highly expressed in kidney, skeletal muscle, liver, lung, heart and brain.
  • 數據庫鏈接：


主站蜘蛛池模板： 搡老岳熟女国产熟妇| 亚洲一区精品无码色成人| 国产亚洲日韩在线a不卡| 中文字幕一区二区三区乱码 | 亚洲色欲色欲www在线丝| 天天躁夜夜躁狠狠眼泪| 东北少妇不戴套对白第一次 | 久热这里只有精品99| 国产一区丝袜在线播放| 人人爽天天碰狠狠添| 国内久久婷婷六月综合欲色啪| 中国少妇内射xxxhd免费| 国产特黄级aaaaa片免| 欧美人与动人物牲交免费观看久久| 亚洲中文字幕无码av| 色天天天综合色天天| 男女啪啪免费观看的网址| 国产免费一区二区三区不卡| 亚洲综合成人av一区在线观看| 熟妇人妻av中文字幕老熟妇| 亚洲老妇色熟女老太| 国产综合色在线视频区| а√天堂www在线а√天堂视频 | 四虎国产精品免费久久久| 国产精品爆乳在线播放第一人称| 国产女人高潮嗷嗷嗷叫| 天堂久久天堂av色综合| 图片区小说区av区| 黑人巨大精品欧美| 国产精品天干天干有线观看| 97色偷偷色噜噜狠狠爱网站97| 亚洲色大成网站在线| 九九热久久只有精品2| 亚洲国产福利一区二区三区| 日日碰狠狠添天天爽无码| 精品久久久久久国产| 日本熟妇大乳| 无码手机线免费观看| 久久久肥妇熟女ⅹxxx毛片| 色狠狠一区二区三区香蕉| 国产亚洲精品久久久久久|