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Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain

  • 中文名稱：
    Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain
  • 貨號：
    CSB-YP850194MRE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain
  • 貨號：
    CSB-EP850194MRE
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain
  • 貨號：
    CSB-EP850194MRE-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain
  • 貨號：
    CSB-BP850194MRE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mesobuthus martensii Lipolysis-activating peptide 1-beta chain
  • 貨號：
    CSB-MP850194MRE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    N/A
  • Uniprot No.：
  • 別名：
    HMG-CoA reductase inhibitor bumarsin; JCH2; Lipolysis-activating peptide 1-beta chain; BmLVP1-beta; LVP1-beta; Neurotoxin KITx; BmKITx; Putative toxin BmKTXLP2
  • 種屬：
    Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    23-94
  • 氨基酸序列
    DSLSPWNE GDTYYGCQRQ TDEFCNKICK LHLASGGSCQ QPAPFVKLCT CQGIDYDNSF FFGALEKQCP KLRG
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    The homodimer inhibits HMG-CoA reductase (HMGCR) (32% of inhibition produced by 0.6 uM), a glycoprotein involved in the control of cholesterol biosynthesis. The inhibitory effects of bumarsin are seen at much lower concentrations (0.6 uM) than that for statins such as atorvastatin (5 mM) and simvastatin (10 uM). In addition to inhibition of HMG-CoA reductase, this protein lowers cholesterol levels by inducing steroid hormone synthesis via StAR, and by increasing reverse cholesterol transport mediated by the induction of ABCA1 and APOA1.; The heterodimer non-edited LVP1 induces lipolysis in rat adipocytes. Induction of lipolysis by LVP1 appears to be mediated through the beta-2 adrenergic receptor pathway (ADRB2).; The monomer edited version, named BmKITx, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Lipo-B family
  • 組織特異性：
    Expressed by the venom gland.


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