在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Macaca fascicularis Tumor necrosis factor alpha-induced protein 3 (TNFAIP3), partial

Recombinant Macaca fascicularis Tumor necrosis factor alpha-induced protein 3 (TNFAIP3), partial

  • 中文名稱：
    獼猴TNFAIP3重組蛋白
  • 貨號：
    CSB-YP687038MOV
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    獼猴TNFAIP3重組蛋白
  • 貨號：
    CSB-EP687038MOV
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    獼猴TNFAIP3重組蛋白
  • 貨號：
    CSB-EP687038MOV-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    獼猴TNFAIP3重組蛋白
  • 貨號：
    CSB-BP687038MOV
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    獼猴TNFAIP3重組蛋白
  • 貨號：
    CSB-MP687038MOV
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TNFAIP3; QtsA-11293; Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; EC 2.3.2.-; EC 3.4.19.12) [Cleaved into: A20p50; A20p37]
  • 種屬：
    Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. In cooperation with TAX1BP1 promotes disassembly of E2-E3 ubiquitin protein ligase complexes in IL-1R and TNFR-1 pathways; affected are at least E3 ligases TRAF6, TRAF2 and BIRC2, and E2 ubiquitin-conjugating enzymes UBE2N and UBE2D3. In cooperation with TAX1BP1 promotes ubiquitination of UBE2N and proteasomal degradation of UBE2N and UBE2D3. Upon TNF stimulation, deubiquitinates 'Lys-63'-polyubiquitin chains on RIPK1 and catalyzes the formation of 'Lys-48'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Deubiquitinates TRAF6 probably acting on 'Lys-63'-linked polyubiquitin. Upon T-cell receptor (TCR)-mediated T-cell activation, deubiquitinates 'Lys-63'-polyubiquitin chains on MALT1 thereby mediating disassociation of the CBM (CARD11:BCL10:MALT1) and IKK complexes and preventing sustained IKK activation. Deubiquitinates NEMO/IKBKG; the function is facilitated by TNIP1 and leads to inhibition of NF-kappa-B activation. Upon stimulation by bacterial peptidoglycans, probably deubiquitinates RIPK2. Can also inhibit I-kappa-B-kinase (IKK) through a non-catalytic mechanism which involves polyubiquitin; polyubiquitin promotes association with IKBKG and prevents IKK MAP3K7-mediated phosphorylation. Targets TRAF2 for lysosomal degradation. In vitro able to deubiquitinate 'Lys-11'-, 'Lys-48'- and 'Lys-63' polyubiquitin chains. Inhibitor of programmed cell death. Has a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.
  • 亞細胞定位：
    Cytoplasm. Nucleus. Lysosome.; [A20p50]: Cytoplasm.
  • 蛋白家族：
    Peptidase C64 family
  • 數據庫鏈接：

    KEGG: mcf:101867362

    UniGene: Mfa.6768



主站蜘蛛池模板： 色婷婷综合和线在线| 少妇太爽了在线观看免费视频| 久久久久无码国产精品一区 | 亚洲熟妇无码一区二区三区导航| 欧洲美熟女乱又伦免费视频| 国产美女视频免费观看网址| 开心婷婷五月激情综合社区| 国产亚洲一区二区在线观看| 樱花草在线社区www韩国| 人人做人人爽久久久精品| 国产成人综合日韩精品无码不卡 | 亚洲国产精品无码一线岛国| 加勒比无码人妻东京热| 久久久一本精品久久精品六六| 久久久久成人精品无码中文字幕| 国产手机在线精品| 久久www免费人成人片| av永久天堂一区| 丰满熟妇被猛烈进入高清片| 无码高潮少妇毛多水多水免费 | 一本色综合亚洲精品蜜桃冫| 国产色在线 | 亚洲| 午夜影视啪啪免费体验区入口 | 老色鬼永久视频网站| 亚洲国产成人久久综合碰碰| 亚洲精品nv久久久久久久久久| 亚洲s色大片在线观看| 日本妇人成熟免费中文字幕| 亚洲精品色情app在线下载观看| 精品人妻av区乱码| 亚洲欧美日韩综合在线一| 最新国产精品无码| 乱中年女人伦av三区| 国产精品久久久久久吹潮| 亚洲另类欧美综合在线| 亚洲 日韩 国产 有码 不卡 | 国色天香天天影院综合网| 国产亚洲精品自在久久蜜tv | 99精品国产一区二区三区a片| 看免费真人视频网站| 日产无码中文字幕av|