在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Macaca fascicularis Mu-type opioid receptor (OPRM1), partial

  • 中文名稱:
    獼猴OPRM1重組蛋白
  • 貨號(hào):
    CSB-YP842565MOV1
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    獼猴OPRM1重組蛋白
  • 貨號(hào):
    CSB-EP842565MOV1
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    獼猴OPRM1重組蛋白
  • 貨號(hào):
    CSB-EP842565MOV1-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    獼猴OPRM1重組蛋白
  • 貨號(hào):
    CSB-BP842565MOV1
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    獼猴OPRM1重組蛋白
  • 貨號(hào):
    CSB-MP842565MOV1
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1
  • 種屬:
    Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1, and to a lesser extent to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4. Phosphorylation by members of the GPRK subfamily of Ser/Thr protein kinases and association with beta-arrestins is involved in short-term receptor desensitization. Beta-arrestins associate with the GPRK-phosphorylated receptor and uncouple it from the G-protein thus terminating signal transduction. The phosphorylated receptor is internalized through endocytosis via clathrin-coated pits which involves beta-arrestins. The activation of the ERK pathway occurs either in a G-protein-dependent or a beta-arrestin-dependent manner and is regulated by agonist-specific receptor phosphorylation. Acts as a class A G-protein coupled receptor (GPCR) which dissociates from beta-arrestin at or near the plasma membrane and undergoes rapid recycling. Receptor down-regulation pathways are varying with the agonist and occur dependent or independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling. Heterooligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. Involved in neurogenesis.
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: mcf:102123390

    UniGene: Mfa.9401



主站蜘蛛池模板: 漂亮人妻被中出中文字幕| 亚洲国产成人久久一区久久 | 最新国产麻豆aⅴ精品无码| 欧美老妇与禽交| 亚洲日本中文字幕天天更新| 国产精品久线在线观看| 丰满少妇人妻久久久久久| 综合激情亚洲丁香社区| 无遮挡免费高清羞羞视频| 激情人妻另类人妻伦| 国产人妻人伦精品1国产| 末发育女av片一区二区| 717影院理论午夜伦八戒| 乌克兰少妇videos高潮| 毛茸茸的中国女bbw| 亚洲人成网站18禁止大| 亚洲中文字幕无码av在线 | 欧美亚洲国产成人一区二区三区 | 亚洲国产精品久久人人爱| 国产av区男人的天堂| 综合自拍亚洲综合图区高清| 国产亚洲精品精品精品| 中文字幕一区二区人妻电影| 女乱高潮久久久久久爽爽| 久青青在线观看视频国产 | 激情射精爽到偷偷c视频无码| 欧美与黑人午夜性猛交久久久| 亚洲欧洲日产国码久在线| 亚洲图欧洲图自拍另类高清| 国产精品丝袜高跟鞋| 无码熟妇人妻av在线影片| 国内精品久久久久久久影视| 久九九精品免费视频| 少妇仑乱a毛片| 男女性杂交内射妇女bbwxz| 亚洲婷婷开心色四房播播| 夜夜夜夜猛噜噜噜噜噜| √最新版天堂资源网在线| 国产精品国语对白露脸在线播放 | 大香伊蕉在人线国产最新75| 久久亚洲国产精品五月天婷|