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  4. Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY (codY)

Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY (codY)

  • 中文名稱：
    Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY(codY)
  • 貨號：
    CSB-YP841496LPY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY(codY)
  • 貨號：
    CSB-EP841496LPY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY(codY)
  • 貨號：
    CSB-EP841496LPY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY(codY)
  • 貨號：
    CSB-BP841496LPY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Listeria monocytogenes serovar 1/2a GTP-sensing transcriptional pleiotropic repressor CodY(codY)
  • 貨號：
    CSB-MP841496LPY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    codY
  • Uniprot No.：
  • 別名：
    codY; lmo1280; GTP-sensing transcriptional pleiotropic repressor CodY
  • 種屬：
    Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-259
  • 氨基酸序列
    MTLLEKTRKI NAMLQNAAGK TVNFKEMADT LTDVIEANTY IVSRKGKLLG YSEALPIEND RMKQMLTERQ FPEEYTQSLF NVGETSSNLE VSSQYTAFPI ENSELFTKGL TTIVPIVGGG ERLGTLILSR LESNFTDDDL LLAEYGGTVV GMEILHEKAE EIEEEARSRA VVQMAISSLS YSELEAIEHI FDELNGKEGL LVASKIADRV GITRSVIVNA LRKLESAGVI DSRSLGMKGT FIRVLNDKFL VELEKLKNN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.
  • 基因功能參考文獻：
    1. The results of this study suggest that elevated c-di-GMP levels decrease the activity of the coordinator of metabolism and virulence, CodY, possibly via lower GTP levels, and that decreased CodY activity suppresses L. monocytogenes virulence by the decreased expression of the PrfA virulence regulon. PMID: 29229701
    2. study provides new data on importance of the RelA & CodY systems in the adaptation of L. monocytogenes to nutritionally exacting environments encountered during infection; first direct evidence that the activity of CodY influences the outcome of infection PMID: 17302820
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    CodY family
  • 數據庫鏈接：

    KEGG: lmo:lmo1280

    STRING: 169963.lmo1280



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