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  4. Recombinant Lactococcus lactis subsp. lactis Formamidopyrimidine-DNA glycosylase (mutM)

Recombinant Lactococcus lactis subsp. lactis Formamidopyrimidine-DNA glycosylase (mutM)

  • 中文名稱：
    乳酸乳球菌亞屬。乳酸mutM重組蛋白
  • 貨號：
    CSB-YP861348LNG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    乳酸乳球菌亞屬。乳酸mutM重組蛋白
  • 貨號：
    CSB-EP861348LNG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    乳酸乳球菌亞屬。乳酸mutM重組蛋白
  • 貨號：
    CSB-EP861348LNG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    乳酸乳球菌亞屬。乳酸mutM重組蛋白
  • 貨號：
    CSB-BP861348LNG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    乳酸乳球菌亞屬。乳酸mutM重組蛋白
  • 貨號：
    CSB-MP861348LNG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    mutM
  • Uniprot No.：
  • 別名：
    mutM; fpg; LL0353; L0271Formamidopyrimidine-DNA glycosylase; Fapy-DNA glycosylase; EC 3.2.2.23; DNA-(apurinic or apyrimidinic site) lyase MutM; AP lyase MutM; EC 4.2.99.18
  • 種屬：
    Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-272
  • 氨基酸序列
    PELPEVETV RRELEKRIVG QKIVSIEATY PRMVLTGFEQ LKKELTGKTI HGISRRGKYL IFEIGEKDRL ISHLRMEGKY RLASLNVPME KHDHLALKFT DEQLIYADVR KFGTWELIST DQVLPYFLKK NIGPEPTYET FDEQIFREKL QKSTKKIKPF LLEQTLVAGL GNIYVDEVLW LAKIHPEKVA NQLTESSIHL LHDSIIEILQ KAIKLGGSSI RTYSALGSTG KMQDELRVYG KTGEKCVRCG NEIQKIKVAG RGTHFCPFCQ QK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  • 基因功能參考文獻：
    1. Authors used molecular dynamic simulation to model interactions in the pre-catalytic complex of Lactococcus lactis Fpg with DNA containing oxoG opposite C or A, the latter in either syn or anti conformation. PMID: 28482831
  • 蛋白家族：
    FPG family
  • 數據庫鏈接：

    KEGG: lla:L0271

    STRING: 272623.L0271



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