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  4. Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6 (LSM6)

Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6 (LSM6)

  • 中文名稱：
    Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6(LSM6)
  • 貨號：
    CSB-YP013209LLZ
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6(LSM6)
  • 貨號：
    CSB-EP013209LLZ
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6(LSM6)
  • 貨號：
    CSB-EP013209LLZ-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6(LSM6)
  • 貨號：
    CSB-BP013209LLZ
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Laccaria bicolor U6 snRNA-associated Sm-like protein LSm6(LSM6)
  • 貨號：
    CSB-MP013209LLZ
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    LSM6
  • Uniprot No.：
  • 別名：
    LSM6; LACBIDRAFT_180652U6 snRNA-associated Sm-like protein LSm6
  • 種屬：
    Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-99
  • 氨基酸序列
    MDNSPPPPSN ESPPPQPPPP QATHTGSPTD FLKGVVGKRV IVRLTSGVDY RGLLSCLDGY MNIALEQTEE HVNGVVTNRY GDAFIRGNNV LYISAAEPI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    SnRNP Sm proteins family, SmF/LSm6 subfamily
  • 數據庫鏈接：


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