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Recombinant Kinetochore null protein 1 (knl-1), partial

  • 中文名稱:
    秀麗隱桿線蟲knl-1重組蛋白
  • 貨號:
    CSB-YP327305CXY
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲knl-1重組蛋白
  • 貨號:
    CSB-EP327305CXY
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲knl-1重組蛋白
  • 貨號:
    CSB-EP327305CXY-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲knl-1重組蛋白
  • 貨號:
    CSB-BP327305CXY
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲knl-1重組蛋白
  • 貨號:
    CSB-MP327305CXY
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    knl-1
  • Uniprot No.:
  • 別名:
    knl-1; C02F5.1Kinetochore null protein 1
  • 種屬:
    Caenorhabditis elegans
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division. Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy. Has a role in the correct localization of the spindly-like protein spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1 to kinetochores. Required for the recruitment of spindle-assembly checkpoint components bub-1 and mdf-1/2 to unattached kinetochores.
  • 基因功能參考文獻:
    1. Data indicate that microtubule-associated proteins KNL-1 oligomerization may coordinate with other kinetochore activities to ensure the proper organization, function, and sensory capabilities of the kinetochore-microtubule attachment. PMID: 25411336
    2. KNL-1 plays a central role in translating the initiation of kinetochore assembly PMID: 14522947
  • 亞細胞定位:
    Cytoplasm, cell cortex. Chromosome, centromere, kinetochore.
  • 數(shù)據(jù)庫鏈接:

    KEGG: cel:CELE_C02F5.1

    STRING: 6239.C02F5.1

    UniGene: Cel.7545



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