在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Influenza B virus Nucleoprotein (NP)

In Stock
  • 中文名稱:
    Recombinant Influenza B virus Nucleoprotein(NP)
  • 貨號:
    CSB-BP361330IJK
  • 規格:
    ¥3168
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    NP
  • Uniprot No.:
  • 別名:
    NP; Nucleoprotein; Nucleocapsid protein; Protein N
  • 種屬:
    Influenza B virus (strain B/Lee/1940)
  • 蛋白長度:
    Full Length
  • 來源:
    Baculovirus
  • 分子量:
    64.3kDa
  • 表達區域:
    1-560aa
  • 氨基酸序列
    MSNMDIDSINTGTIDKTPEELTPGTSGATRPIIKPATLAPPSNKRTRNPSPERTTTSSETDIGRKIQKKQTPTEIKKSVYKMVVKLGEFYNQMMVKAGLNDDMERNLIQNAQAVERILLAATDDKKTEYQKKRNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIKITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKGLKRVGLDPSLISTFAGSTLPRRSGTTGVAIKGGGTLVDEAIRFIGRAMADRGLLRDIKAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISIYAKIPQLGFNTEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDLRVLSALTGTEFKPRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVSGEGGSGQISCSPVFAVERPIALSKQAVRRMLSMNVEGRDADVKGNLLKMMNDSMAKKTSGNAFIGKKMFQISDKNKVNPIEIPIKQTIPNFFFGRDTAEDYDDLDY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    Intact influenza B virus nucleoprotein (NP) cDNA (1-560aa) with an N-terminal 10xHis-tag was expressed in the Baculovirus cells. The forming protein is the recombinant full-length influenza B virus NP protein. The purity of this protein is greater than 85% determined by SDS-PAGE. Under reducing conditions, the gel showed a molecular weight band of about 65 kDa. In-stock influenza B virus NP proteins are offered now. In addition to producing specific antibodies, this recombinant influenza B virus NP protein may be used in the studies of microbiology.

    Nucleoprotein (NP) is the predominant component of the influenza virus ribonucleoprotein. It is highly conserved among each type of influenza viruses. Alice Labaronne etc. demonstrated that the NP of influenza B virus has a long N-terminal tail of 70 residues with intrinsic flexibility. This tail contains the Nuclear Location Signal (NLS). And NP is imported into the nucleus by the importin-α/β pathway via direct interaction with importin-α isoforms. In addition, NP is the potential target for a universal influenza vaccine.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
  • 基因功能參考文獻:
    1. Results show that the N terminus is involved in the formation of both higher homo-oligomers of BNP and BNP-RNA complex. PMID: 26368391
  • 亞細胞定位:
    Virion. Host nucleus.
  • 蛋白家族:
    Influenza viruses nucleoprotein family
  • 數據庫鏈接:

    KEGG: vg:26824002



主站蜘蛛池模板: 无码国产偷倩在线播放| 天天干天天射天天操| 久久er99热精品一区二区| 久久精品国产精油按摩| 国产av老师丝袜美腿丝袜| 精品国产一区二区三区av色诱| 日韩吃奶摸下aa片免费观看| 精品深夜av无码一区二区| 免费无码av片在线观看| 性xxx欧美老妇5060.70| 久久精品视频在线看| 国产女人被狂躁到高潮小说| 亚洲女女女同性video| 亚洲国产中文曰韩丝袜| 超薄肉色丝袜一区二区| 成人欧美一区二区三区黑人| 亚洲综合色区无码专区| 久久精品国产国产精品四凭| 手机在线看永久av片免费| 无码人妻啪啪一区二区| 熟女毛多熟妇人妻在线视频| 免费无码成人av片在线| 亚洲日韩一区精品射精| 欧美大浪妇猛交饥渴大叫| 亚洲性色av一区二区三区| 韩国精品久久久久久无码| 色欲狠狠躁天天躁无码中文字幕| 国产成a人亚洲精品无码樱花| 亚洲欧美国产双大乳头| 四虎影库久免费视频| 18禁在线永久免费观看| 亚洲中文字幕乱码电影| 欧美乱人伦视频在线| 夜夜爽日日澡人人添| 男女裸交免费无遮挡全过程| 国产福利男女xx00视频| 高清免费精品国自产拍| 无码丰满熟妇| 久久精品国产9久久综合| 最美女人体内射精一区二区| 欧美 变态 另类 人妖|