在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Influenza B virus Nucleoprotein (NP)

In Stock
  • 中文名稱:
    Recombinant Influenza B virus Nucleoprotein(NP)
  • 貨號:
    CSB-BP361330IJK
  • 規格:
    ¥3168
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    NP
  • Uniprot No.:
  • 別名:
    NP; Nucleoprotein; Nucleocapsid protein; Protein N
  • 種屬:
    Influenza B virus (strain B/Lee/1940)
  • 蛋白長度:
    Full Length
  • 來源:
    Baculovirus
  • 分子量:
    64.3kDa
  • 表達區域:
    1-560aa
  • 氨基酸序列
    MSNMDIDSINTGTIDKTPEELTPGTSGATRPIIKPATLAPPSNKRTRNPSPERTTTSSETDIGRKIQKKQTPTEIKKSVYKMVVKLGEFYNQMMVKAGLNDDMERNLIQNAQAVERILLAATDDKKTEYQKKRNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIKITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKGLKRVGLDPSLISTFAGSTLPRRSGTTGVAIKGGGTLVDEAIRFIGRAMADRGLLRDIKAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISIYAKIPQLGFNTEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDLRVLSALTGTEFKPRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVSGEGGSGQISCSPVFAVERPIALSKQAVRRMLSMNVEGRDADVKGNLLKMMNDSMAKKTSGNAFIGKKMFQISDKNKVNPIEIPIKQTIPNFFFGRDTAEDYDDLDY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    Intact influenza B virus nucleoprotein (NP) cDNA (1-560aa) with an N-terminal 10xHis-tag was expressed in the Baculovirus cells. The forming protein is the recombinant full-length influenza B virus NP protein. The purity of this protein is greater than 85% determined by SDS-PAGE. Under reducing conditions, the gel showed a molecular weight band of about 65 kDa. In-stock influenza B virus NP proteins are offered now. In addition to producing specific antibodies, this recombinant influenza B virus NP protein may be used in the studies of microbiology.

    Nucleoprotein (NP) is the predominant component of the influenza virus ribonucleoprotein. It is highly conserved among each type of influenza viruses. Alice Labaronne etc. demonstrated that the NP of influenza B virus has a long N-terminal tail of 70 residues with intrinsic flexibility. This tail contains the Nuclear Location Signal (NLS). And NP is imported into the nucleus by the importin-α/β pathway via direct interaction with importin-α isoforms. In addition, NP is the potential target for a universal influenza vaccine.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
  • 基因功能參考文獻:
    1. Results show that the N terminus is involved in the formation of both higher homo-oligomers of BNP and BNP-RNA complex. PMID: 26368391
  • 亞細胞定位:
    Virion. Host nucleus.
  • 蛋白家族:
    Influenza viruses nucleoprotein family
  • 數據庫鏈接:

    KEGG: vg:26824002



主站蜘蛛池模板: 国产真人无遮挡作爱免费视频| 国产午夜理论片不卡| 亚洲精品国产综合麻豆久久99| 欧美videos另类极品| 无码无套少妇18p在线直播| 欧美成年网站色a| 一个人看的www视频免费观看 | 亚洲 自拍 色综合图区av| 欧美精品18videosex性欧| 熟女少妇丰满一区二区| 欧美老熟妇牲交| 国产精品无码素人福利 | 黄网站欧美内射| 国产精品无码a∨精品影院app| 国产农村黄aaaaa特黄av毛片 | 国内女人喷潮完整视频| 推油少妇久久99久久99久久| 国产探花在线精品一区二区| 久久久久久成人综合网| 国产区精品福利在线社区| 国产人妻精品一区二区三区不卡| 久久精品中文騷妇女内射| 成 人 综合 亚洲另类| 亚洲精品无码永久中文字幕| 无码乱码av天堂一区二区| 45分钟免费真人视频| 久久99精品久久久久久齐齐| 日韩av中文无码影院| 国产成人精品亚洲777人妖| 国产成人无码专区| av狠狠色超碰丁香婷婷综合久久| 亚洲最大无码av网站观看| 久久久久久亚洲精品a片成人| 一本一本久久a久久精品综合麻豆| а天堂中文在线官网| 人妻精品久久久久中文字幕| 日本一卡2卡3卡4卡5卡精品视频| 欧美性猛交xxxx乱大交| 福利姬液液酱喷水| 亚洲香蕉网久久综合影视| 丰满少妇高潮惨叫久久久|