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  4. Recombinant Influenza A virus Neuraminidase (NA)

Recombinant Influenza A virus Neuraminidase (NA)

  • 中文名稱：
    Recombinant Influenza A virus Neuraminidase(NA)
  • 貨號：
    CSB-YP714923IGT
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Influenza A virus Neuraminidase(NA)
  • 貨號：
    CSB-EP714923IGT
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Influenza A virus Neuraminidase(NA)
  • 貨號：
    CSB-EP714923IGT-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Influenza A virus Neuraminidase(NA)
  • 貨號：
    CSB-BP714923IGT
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Influenza A virus Neuraminidase(NA)
  • 貨號：
    CSB-MP714923IGT
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NA
  • Uniprot No.：
  • 別名：
    NA; Neuraminidase; EC 3.2.1.18; Fragment
  • 種屬：
    Influenza A virus (strain A/Swine/Hong Kong/127/1982 H3N2)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-446
  • 氨基酸序列
    MQIAILVTTV TLHFNQYECD SLADNQVMPC EPIIIERNIT EIIYLTNTTI EKEICPKLME YRNWSRPQCK ITGFAPFSKD NSIRLSAGGD IWVTREPYVS CDPGKCYQFA LGQGTTLDNK HSNDTIHDRI PHRTLLMNEL GVPFHLGTRQ VCIAWSSSSC HDGKAWLHVC VTGDDKNATA SFIYDGRLVD SMGSWSQNIL RTQESECVCI NGTCTVVMTD GSASGRADTR ILFIEEGKIV HISPLSGSAQ HVEECSCYPR YPSVRCICRD NWKGSNRPIV DINIKDYSID SRYVCSGLVG DTPRNNDRSS SSDCKNPNND KGNHGVKGWA FDDGNDVWMG RTISKDSRSG YETFKVIDGW STPNSKSQIN RQVIVDRDNR SGYSGIFSVE SKGCINRCFY VELIRGRKQE TRVWWTSSSI VVFCGTSGTY GKGSWPDGAN INFMPI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
  • 亞細胞定位：
    Virion membrane. Host apical cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyl hydrolase 34 family


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