在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human tRNA (guanine-N (7)-)-methyltransferase subunit WDR4 (WDR4)

  • 中文名稱:
    人WDR4重組蛋白
  • 貨號(hào):
    CSB-YP026021HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人WDR4重組蛋白
  • 貨號(hào):
    CSB-EP026021HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人WDR4重組蛋白
  • 貨號(hào):
    CSB-BP026021HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人WDR4重組蛋白
  • 貨號(hào):
    CSB-MP026021HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    WDR4
  • Uniprot No.:
  • 別名:
    OTTHUMP00000109401; OTTHUMP00000109402; TRM82; tRNA (guanine N(7) ) methyltransferase subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat containing protein 4; WD repeat protein 4; WD repeat protein domain 4 protein isoform 2; WD repeat-containing protein 4; wdr4; WDR4_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-412
  • 氨基酸序列
    AGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKKSQENKGEDAPLDQGS GAILASTFSKSGSYFALTDDSKRLILFRTKPWQCLSVRTVARRCTALTFIASEEKVLVAD KSGDVYSFSVLEPHGCGRLELGHLSMLLDVAVSPDDRFILTADRDEKIRVSWAAAPHSIE SFCLGHTEFVSRISVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQELVDPQAP QKFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQQLVYRQQLAFQHQVWDVAFEETQ GLWVLQDCQEAPLVLYRPVGDQWQSVPESTVLKKVSGVLRGNWAMLEGSAGADASFSSLY KATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHAKKMRPGEATLSC
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Non-catalytic component of a methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs). In the methyltransferase complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Also required for the formation of N(7)-methylguanine at internal sites in a subset of mRNAs. Also required for methylation of a specific subset of miRNAs, such as let-7. Independently of METTL1, also plays a role in genome stability: localizes at the DNA replication site and regulates endonucleolytic activities of FEN1.
  • 基因功能參考文獻(xiàn):
    1. WDR4 is an oncoprotein that negatively regulates PML via ubiquitination to promote lung cancer progression by fostering an immunosuppressive and prometastatic tumor microenvironment PMID: 28691927
    2. Combined autozygome/exome analysis revealed a novel missense mutation in WDR4 as the likely causal variant of Primordial dwarfism PMID: 26416026
    3. regulates FEN1's potential DNA cleavage threat near the site of replication PMID: 26751069
  • 亞細(xì)胞定位:
    Nucleus. Chromosome.
  • 蛋白家族:
    WD repeat TRM82 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12756

    OMIM: 605924

    KEGG: hsa:10785

    STRING: 9606.ENSP00000328671

    UniGene: Hs.248815



主站蜘蛛池模板: 欧美视频网站www色| 亚洲精品无码av中文字幕电影网站 | 久久精品国产99久久久| 天天做天天爱夜夜夜爽毛片| 久久婷婷激情综合色综合俺也去| 伊人无码精品久久一区二区| 玩弄人妻少妇老师美妇厨房| 色偷偷色噜噜狠狠网站久久| 国产精品一卡二卡三卡| 久久九九兔免费精品6| 国产亚洲日韩在线a不卡| 妓院一钑片免看黄大片| 国产69精品久久久久人妻刘玥| 国产三级韩国三级日产三级| 精品国产成人高清在线观看| 草色噜噜噜av在线观看香蕉| 欧美又粗又长又爽做受| 国内芒果精品自线一区2021| 亚洲精品乱码久久久久久自慰 | 日产精品久久久久久久| 久久久午夜精品福利内容| 国产精品亚洲w码日韩中文| 国产美女裸身网站免费观看视频| 国产无人区码一码二码三mba | 国产成人午夜精华液| 中文无码成人免费视频在线观看| 国产在线高清亚洲精品二区| 无码毛片一区二区本码视频| 国产伦精品一区二区三区免费| 无码中文av有码中文a| 亚洲 欧美精品suv| 亚洲五月天综合| 精品视频一区二区三区在线观看| 国产综合视频一区二区三区| 色婷婷六月亚洲综合香蕉| 99久久综合狠狠综合久久止| 狠狠色噜噜狠狠狠狠色综合久av| 涩涩鲁亚洲精品一区二区| 毛片免费视频肛交颜射免费视频| 无码中文人妻在线三区| 艳妇乳肉豪妇荡乳在线观看|