在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160 (env), partial

  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160(env) ,partial
  • 貨號:
    CSB-YP758854HLS
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160(env) ,partial
  • 貨號:
    CSB-EP758854HLS
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160(env) ,partial
  • 貨號:
    CSB-EP758854HLS-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160(env) ,partial
  • 貨號:
    CSB-BP758854HLS
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group O Envelope glycoprotein gp160(env) ,partial
  • 貨號:
    CSB-MP758854HLS
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    env
  • Uniprot No.:
  • 別名:
    env; Envelope glycoprotein gp160; Env polyprotein) [Cleaved into: Surface protein gp120; SU; Glycoprotein 120; gp120); Transmembrane protein gp41; TM; Glycoprotein 41; gp41)]
  • 種屬:
    Human immunodeficiency virus type 1 group O (isolate ANT70) (HIV-1)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.; Attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. Acts as a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses. These interactions allow capture of viral particles at mucosal surfaces by these cells and subsequent transmission to permissive cells. HIV subverts the migration properties of dendritic cells to gain access to CD4+ T-cells in lymph nodes. Virus transmission to permissive T-cells occurs either in trans (without DCs infection, through viral capture and transmission), or in cis (following DCs productive infection, through the usual CD4-gp120 interaction), thereby inducing a robust infection. In trans infection, bound virions remain infectious over days and it is proposed that they are not degraded, but protected in non-lysosomal acidic organelles within the DCs close to the cell membrane thus contributing to the viral infectious potential during DCs' migration from the periphery to the lymphoid tissues. On arrival at lymphoid tissues, intact virions recycle back to DCs' cell surface allowing virus transmission to CD4+ T-cells.; Acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane. The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
  • 亞細胞定位:
    [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein.; [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    HIV-1 env protein family


主站蜘蛛池模板: 日本丰满老妇bbw| 亚洲精品无码mⅴ在线观看| 日本丰满熟妇乱子伦| 国产高潮流白浆视频| 视频分类 国内精品| 亚洲欧美日韩综合一区二区 | 免费1级a做爰片观看| 国产成人免费永久播放视频平台| 97av麻豆蜜桃一区二区| 妓院一钑片免看黄大片| av人摸人人人澡人人超碰小说 | 国产制服丝袜亚洲高清| 裸体丰满白嫩大尺度尤物| 欧美人妻精品一区二区三区 | 女人夜夜春高潮爽a∨片| 内射老阿姨1区2区3区4区| 男阳茎进女阳道视频大全| 青青青青国产免费线在线观看| 国产片av国语在线观麻豆| 国产亚洲精品字幕在线观看| 精品人妻少妇一区二区三区在线| 狠狠躁夜夜躁人人爽天天古典| 宅男色影视亚洲人在线| 少妇粉嫩小泬白浆流出| 精品无码一区二区三区不卡| 国产成人av片无码免费| 亚洲日韩亚洲另类| 亚洲日韩中文字幕一区| 三上悠亚的av片在线无码| 真人一进一出120秒试看| 中文字幕人妻熟女人妻| 欧美丰满熟妇xxxxx| 欧洲亚洲国产成人综合色婷婷| 亚洲性无码av在线dvd| 激情综合色综合啪啪五月丁香| 欧美交a欧美精品喷水| 久青青在线观看视频国产 | 国产成人精品a视频免费福利| 99香蕉国产精品偷在线观看| 少妇的丰满3中文字幕| 国产熟妇精品高潮一区二区三区 |