在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev (rev)

Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev (rev)

  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev(rev)
  • 貨號：
    CSB-YP323053HLJ
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev(rev)
  • 貨號：
    CSB-EP323053HLJ
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev(rev)
  • 貨號：
    CSB-EP323053HLJ-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev(rev)
  • 貨號：
    CSB-BP323053HLJ
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human immunodeficiency virus type 1 group M subtype D Protein Rev(rev)
  • 貨號：
    CSB-MP323053HLJ
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    rev
  • Uniprot No.：
  • 別名：
    rev; Protein Rev; ART/TRS; Anti-repression transactivator; Regulator of expression of viral proteins
  • 種屬：
    Human immunodeficiency virus type 1 group M subtype D (isolate NDK) (HIV-1)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-116
  • 氨基酸序列
    MAGRSGDSDE NLLKAIRLIK FLYQSNPPPS PEGTRQARRN RRRRWRARQR QIHSIGERII CTFLGRPEEP VPLQLPPLER LNLNCSEDCG TSGTQGVGSP QIPVEPPAVL ESGTEE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus. In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs. Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface. Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex. Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export. Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import. The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
  • 亞細胞定位：
    Host nucleus, host nucleolus. Host cytoplasm.
  • 蛋白家族：
    HIV-1 REV protein family


主站蜘蛛池模板： 老司机午夜免费精品视频| 国产人妻大战黑人20p| 樱桃视频影视在线观看免费| 国产乡下妇女做爰| 秋霞国产成人精品午夜视频app| 国产成人亚洲精品无码最新| 色婷婷亚洲一区二区综合| 香港三日本三级少妇三级66| 边添小泬边狠狠躁视频| 四虎影视在线影院在线观看| 国产八十老太另类| 67194熟妇在线直接进入| 人妻无码第一区二区三区| 国产精品久久久久9999赢消| 黄网站色视频免费国产| 国产免费无遮挡吸乳视频在线观看| 午夜大片男女免费观看爽爽爽尤物 | 妺妺窝人体色www在线下载| 亚洲精品国产熟女久久久| 9l国产精品久久久久麻豆| 中文字字幕在线成人av电影| 国产精品99久久精品爆乳| 亚洲日韩高清在线亚洲专区| 国产高跟黑色丝袜在线| 欧美色欧美亚洲高清在线视频| 天堂а√中文在线官网| 正在播放国产真实哭都没用| 久久www成人免费直播| 国产精品va无码免费| 边添小泬边狠狠躁视频| 日本免费一区二区三区日本| 亚洲色欲色欲www在线看| av免费不卡国产观看| 国产成人精品午夜福利在线观看| 国产三级视频在线播放线观看 | 少妇无码av无码去区钱| 野花社区视频www官网| 国产免费一区二区三区免费视频| 最近高清中文在线字幕在线观看1| 亚洲裸男gv网站| 欧美老妇与zozozo交|