在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human immunodeficiency virus type 1 group M subtype C Protein Rev (rev)

  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype C Protein Rev(rev)
  • 貨號:
    CSB-EP748326HDAH
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    rev
  • Uniprot No.:
  • 別名:
    rev; Protein Rev; ART/TRS; Anti-repression transactivator; Regulator of expression of viral proteins
  • 種屬:
    Human immunodeficiency virus type 1 group M subtype C (isolate ETH2220) (HIV-1)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    38.7 kDa
  • 表達區域:
    1-107aa
  • 氨基酸序列
    MAGRSGDSDEELLKAVRIIKILYQSNPYPTPEGTRQARRNRRRRWRARQRQIHTLSERILSNFLGRPAEPVPLQLPPLERLNLDCSEDSGTSGTQQSQGTTEGVGNP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    13-23 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus. In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs. Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface. Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex. Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export. Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import. The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
  • 亞細胞定位:
    Host nucleus, host nucleolus. Host cytoplasm.
  • 蛋白家族:
    HIV-1 REV protein family


主站蜘蛛池模板: 国产亚洲精品久久777777| 欧美人与动zozo在线播放| 午夜性刺激在线视频免费| 国产精品无码av在线播放| 久碰久摸久看视频在线观看| 正在播放东北夫妻内射| 九九热久久只有精品2| 国产精品丝袜高跟鞋| 亚洲不卡中文字幕无码| 国产成人一区二区三区在线观看 | 国产揄拍国产精品| 亚洲漂亮少妇毛茸茸| 69综合精品国产二区无码| 老司机亚洲精品影院| 精品无码av一区二区三区| 免费人成网站视频在线观看国内| 亚洲欧美成人精品香蕉网| 大肉大捧一进一出好爽视频| 男女裸体下面进入的免费视频 | 国产剧情无码播放在线观看| 亚洲熟妇无码一区二区三区| 狠狠色综合网站久久久久久久| 人妻少妇伦在线麻豆m电影| 人妻av乱片av出轨av| 国产无遮挡裸体免费视频在线观看 | 中国老熟女重囗味hdxx| 日韩av无码国产精品| 波多野结衣爽到高潮大喷| 欧美va久久久噜噜噜久久| 日韩精品一区二区三区在线观看| 熟妇熟女乱妇乱女网站| 中文字幕av无码人妻| 极品少妇被猛的白浆直喷白浆| 亚洲精品久久久久久中文字幕 | 夜夜爽夜夜叫夜夜高潮漏水| 西西人体大胆扒开下部337卩| 人妻熟妇乱又伦精品视频| 狼色精品人妻在线视频| 精品一区二区国产在线观看| 无码喷水一区二区浪潮av| 久久精品国产99国产精品亚洲 |